5'-O-DMT-ibu-rG
Based on 1 Customer Validation
5'-O-DMT-ibu-rG (5'-O-DMT-N2-isobutyrylguanosine) is a chemically modified guanosine derivative that can be used as a novel DNA-binding molecule for the development of effective and selective anti-cancer agents.
For research use only. We do not sell to patients.
- Purity: 95.39%
- CAS No.: 81246-83-5
- Formula: C35H37N5O8
- Molecular Weight:655.70
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
5'-O-DMT-ibu-rG, as a phosphoramidite precursor or a protected nucleoside monomer, can be used for solid-phase synthesis of oligonucleotides (such as siRNA, antisense oligonucleotides).
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 81246-83-5
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Appearance Solid
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Molecular Weight 655.70
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Formula C35H37N5O8
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Color White to off-white
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SMILES
O[C@H]1[C@@H](O)[C@H](N2C=NC3=C2N=C(NC(C(C)C)=O)NC3=O)O[C@@H]1COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6
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Synonyms
5'-O-DMT-N2-isobutyrylguanosine
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 175 mg/mL (266.89 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.5251 mL | 7.6254 mL | 15.2509 mL | 38.1272 mL |
| 5 mM | 0.3050 mL | 1.5251 mL | 3.0502 mL | 7.6254 mL | |
| 10 mM | 0.1525 mL | 0.7625 mL | 1.5251 mL | 3.8127 mL | |
| 15 mM | 0.1017 mL | 0.5084 mL | 1.0167 mL | 2.5418 mL | |
| 20 mM | 0.0763 mL | 0.3813 mL | 0.7625 mL | 1.9064 mL | |
| 25 mM | 0.0610 mL | 0.3050 mL | 0.6100 mL | 1.5251 mL | |
| 30 mM | 0.0508 mL | 0.2542 mL | 0.5084 mL | 1.2709 mL | |
| 40 mM | 0.0381 mL | 0.1906 mL | 0.3813 mL | 0.9532 mL | |
| 50 mM | 0.0305 mL | 0.1525 mL | 0.3050 mL | 0.7625 mL | |
| 60 mM | 0.0254 mL | 0.1271 mL | 0.2542 mL | 0.6355 mL | |
| 80 mM | 0.0191 mL | 0.0953 mL | 0.1906 mL | 0.4766 mL | |
| 100 mM | 0.0153 mL | 0.0763 mL | 0.1525 mL | 0.3813 mL |
5'-O-DMT-ibu-rG Related Classifications
HY-43058 Related Classifications
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