1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. 6-Aminopyridine-3-thioamide

6-Aminopyridine-3-thioamide is a compound with anti-tumor activity that can inhibit the activity of specific enzymes, thereby affecting cell proliferation and survival. 6-Aminopyridine-3-thioamide has also been studied for the inhibition of neurodegenerative diseases and has shown the potential to improve neurological function. The structural characteristics of 6-Aminopyridine-3-thioamide make it an important bioactive molecule in compound development.

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6-Aminopyridine-3-thioamide

6-Aminopyridine-3-thioamide Chemical Structure

CAS No. : 53268-33-0

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Description

6-Aminopyridine-3-thioamide is a compound with anti-tumor activity that can inhibit the activity of specific enzymes, thereby affecting cell proliferation and survival. 6-Aminopyridine-3-thioamide has also been studied for the inhibition of neurodegenerative diseases and has shown the potential to improve neurological function. The structural characteristics of 6-Aminopyridine-3-thioamide make it an important bioactive molecule in compound development.

Molecular Weight

153.20

Formula

C6H7N3S

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

S=C(C1=CC=C(N)N=C1)N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (326.37 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.5274 mL 32.6371 mL 65.2742 mL
5 mM 1.3055 mL 6.5274 mL 13.0548 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 6.5274 mL 32.6371 mL 65.2742 mL 163.1854 mL
5 mM 1.3055 mL 6.5274 mL 13.0548 mL 32.6371 mL
10 mM 0.6527 mL 3.2637 mL 6.5274 mL 16.3185 mL
15 mM 0.4352 mL 2.1758 mL 4.3516 mL 10.8790 mL
20 mM 0.3264 mL 1.6319 mL 3.2637 mL 8.1593 mL
25 mM 0.2611 mL 1.3055 mL 2.6110 mL 6.5274 mL
30 mM 0.2176 mL 1.0879 mL 2.1758 mL 5.4395 mL
40 mM 0.1632 mL 0.8159 mL 1.6319 mL 4.0796 mL
50 mM 0.1305 mL 0.6527 mL 1.3055 mL 3.2637 mL
60 mM 0.1088 mL 0.5440 mL 1.0879 mL 2.7198 mL
80 mM 0.0816 mL 0.4080 mL 0.8159 mL 2.0398 mL
100 mM 0.0653 mL 0.3264 mL 0.6527 mL 1.6319 mL
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6-Aminopyridine-3-thioamide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
6-Aminopyridine-3-thioamide
Cat. No.:
HY-W195933
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