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Cat. No.: HY-N15012

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6-O-Demethyl-5-deoxyfusarubin

6-O-Demethyl-5-deoxyfusarubin has the ability of anti-fungal and mycoplasma.

For research use only. We do not sell to patients.

CAS No.: 132899-05-9
Formula: C₁₅H₁₄O₆
Molecular Weight:290.27

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

6-O-Demethyl-5-deoxyfusarubin Chemical Structure

CAS No.: 132899-05-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

6-O-Demethyl-5-deoxyfusarubin has the ability of anti-fungal and mycoplasma^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	>40 μM Compound: 16	Cytotoxicity against human A549 cells incubated for 48 hrs by MTT assay Cytotoxicity against human A549 cells incubated for 48 hrs by MTT assay	[PMID: 32394716]
HeLa	IC₅₀	10.3 μM Compound: 1	Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 96 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 96 hrs by MTT assay	[PMID: 28257197]
KB	IC₅₀	>40 μM Compound: 16	Cytotoxicity against human KB cells incubated for 48 hrs by MTT assay Cytotoxicity against human KB cells incubated for 48 hrs by MTT assay	[PMID: 32394716]
MCF7	IC₅₀	>40 μM Compound: 16	Cytotoxicity against human MCF7 cells incubated for 48 hrs by MTT assay Cytotoxicity against human MCF7 cells incubated for 48 hrs by MTT assay	[PMID: 32394716]
MDA-MB-231	IC₅₀	30.72 μM Compound: 1	Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 96 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 96 hrs by MTT assay	[PMID: 28257197]
MIA PaCa-2	IC₅₀	20.46 μM Compound: 1	Cytotoxicity against human MIAPaCa2 cells assessed as reduction in cell viability incubated for 96 hrs by MTT assay Cytotoxicity against human MIAPaCa2 cells assessed as reduction in cell viability incubated for 96 hrs by MTT assay	[PMID: 28257197]
NCI-H1975	IC₅₀	27.73 μM Compound: 1	Cytotoxicity against human NCI-H1975 cells assessed as reduction in cell viability incubated for 96 hrs by MTT assay Cytotoxicity against human NCI-H1975 cells assessed as reduction in cell viability incubated for 96 hrs by MTT assay	[PMID: 28257197]
WI-38	IC₅₀	54.34 μM Compound: 1	Cytotoxicity against human WI38 cells assessed as reduction in cell viability incubated for 96 hrs by MTT assay Cytotoxicity against human WI38 cells assessed as reduction in cell viability incubated for 96 hrs by MTT assay	[PMID: 28257197]

Chemical Information

CAS No. 132899-05-9
Molecular Weight 290.27
Formula C₁₅H₁₄O₆
SMILES

O=C1C2=CC(OC)=CC(O)=C2C(C3=C1CC(OC3)(C)O)=O
Structure Classification
- Quinones
- Naphthalene Quinones
Initial Source
- Microorganisms
fungus Nectria haematococca
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. D Parisot, et al. 6-O-demethyl-5-deoxyfusarubin and its anhydro derivative produced by a mutant of the fungus Nectria haematococca blocked in fusarubin biosynthesis. J Antibiot (Tokyo). 1991 Jan;44(1):103-7. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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