8-Aza-2’-deoxyguanosine
Based on 1 Customer Validation
8-Aza-2’-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
For research use only. We do not sell to patients.
- Purity: 99.93%
- CAS No.: 4546-73-0
- Formula: C9H12N6O4
- Molecular Weight:268.23
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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CAS No. 4546-73-0
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Appearance Solid
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Molecular Weight 268.23
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Formula C9H12N6O4
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Color White to off-white
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SMILES
O[C@H]1C[C@H](N2C(N=C(N)NC3=O)=C3N=N2)O[C@@H]1CO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (186.41 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.7281 mL | 18.6407 mL | 37.2814 mL | 93.2036 mL |
| 5 mM | 0.7456 mL | 3.7281 mL | 7.4563 mL | 18.6407 mL | |
| 10 mM | 0.3728 mL | 1.8641 mL | 3.7281 mL | 9.3204 mL | |
| 15 mM | 0.2485 mL | 1.2427 mL | 2.4854 mL | 6.2136 mL | |
| 20 mM | 0.1864 mL | 0.9320 mL | 1.8641 mL | 4.6602 mL | |
| 25 mM | 0.1491 mL | 0.7456 mL | 1.4913 mL | 3.7281 mL | |
| 30 mM | 0.1243 mL | 0.6214 mL | 1.2427 mL | 3.1068 mL | |
| 40 mM | 0.0932 mL | 0.4660 mL | 0.9320 mL | 2.3301 mL | |
| 50 mM | 0.0746 mL | 0.3728 mL | 0.7456 mL | 1.8641 mL | |
| 60 mM | 0.0621 mL | 0.3107 mL | 0.6214 mL | 1.5534 mL | |
| 80 mM | 0.0466 mL | 0.2330 mL | 0.4660 mL | 1.1650 mL | |
| 100 mM | 0.0373 mL | 0.1864 mL | 0.3728 mL | 0.9320 mL |