1. Cell Cycle/DNA Damage Metabolic Enzyme/Protease
  2. DNA/RNA Synthesis Endogenous Metabolite
  3. 8-NH2-ATP

8-NH2-ATP  (Synonyms: 8-Aminoadenosine-5'-O-triphosphate)

Cat. No.: HY-134313
Handling Instructions

8-NH2-ATP, an inactive form of ATP, is produced by 8-NH2-Ado. 8-NH2-Ado is reported to be potent as shown by induction of apoptosis-related cleavage of poly (ADP-ribose) polymerase.

For research use only. We do not sell to patients.

8-NH2-ATP Chemical Structure

8-NH2-ATP Chemical Structure

CAS No. : 35874-49-8

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Description

8-NH2-ATP, an inactive form of ATP, is produced by 8-NH2-Ado. 8-NH2-Ado is reported to be potent as shown by induction of apoptosis-related cleavage of poly (ADP-ribose) polymerase[1][2].

In Vitro

The extensive cellular accumulation of 8-NH2-ATP has an inhibitory effect on both RNA and DNA synthesis in both glucocorticoid-sensitive and glucocorticoid-resistant myeloma cell lines[1][2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

522.20

Formula

C10H17N6O13P3

CAS No.
SMILES

NC(N([C@]([C@@H]([C@@H]1O)O)([H])O[C@@H]1CO[P](O[P](O[P](O)(O)=O)(O)=O)(O)=O)C2=NC=N3)=NC2=C3N

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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8-NH2-ATP
Cat. No.:
HY-134313
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