1. Cell Cycle/DNA Damage
    Metabolic Enzyme/Protease
  2. DNA/RNA Synthesis
    Endogenous Metabolite
  3. 8-NH2-ATP

8-NH2-ATP (Synonyms: 8-Aminoadenosine-5'-O-triphosphate)

Cat. No.: HY-134313
Handling Instructions

8-NH2-ATP, an inactive form of ATP, is produced by 8-NH2-Ado. 8-NH2-Ado is reported to be potent as shown by induction of apoptosis-related cleavage of poly (ADP-ribose) polymerase.

For research use only. We do not sell to patients.

8-NH2-ATP Chemical Structure

8-NH2-ATP Chemical Structure

CAS No. : 35874-49-8

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Description

8-NH2-ATP, an inactive form of ATP, is produced by 8-NH2-Ado. 8-NH2-Ado is reported to be potent as shown by induction of apoptosis-related cleavage of poly (ADP-ribose) polymerase[1][2].

In Vitro

The extensive cellular accumulation of 8-NH2-ATP has an inhibitory effect on both RNA and DNA synthesis in both glucocorticoid-sensitive and glucocorticoid-resistant myeloma cell lines[1][2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

522.20

Formula

C₁₀H₁₇N₆O₁₃P₃

CAS No.
SMILES

NC(N([[email protected]]([[email protected]@H]([[email protected]@H]1O)O)([H])O[[email protected]@H]1CO[P](O[P](O[P](O)(O)=O)(O)=O)(O)=O)C2=NC=N3)=NC2=C3N

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

8-NH2-ATP8-Aminoadenosine-5'-O-triphosphateDNA/RNA SynthesisEndogenous MetaboliteInhibitorinhibitorinhibit

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8-NH2-ATP
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HY-134313
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