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Cat. No.: HY-134313

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8-NH2-ATP

Name: 8-NH2-ATP
Brand: MedChemExpress
SKU: HY-134313
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(Synonyms: 8-Aminoadenosine-5'-O-triphosphate)

8-NH2-ATP, an inactive form of ATP, is produced by 8-NH2-Ado. 8-NH2-Ado is reported to be potent as shown by induction of apoptosis-related cleavage of poly (ADP-ribose) polymerase.

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CAS No.: 35874-49-8
Formule: C₁₀H₁₇N₆O₁₃P₃
Masse moléculaire:522.20

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

8-NH2-ATP Chemical Structure

CAS No.: 35874-49-8

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Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références
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Activité biologique

Description

8-NH2-ATP, an inactive form of ATP, is produced by 8-NH2-Ado. 8-NH2-Ado is reported to be potent as shown by induction of apoptosis-related cleavage of poly (ADP-ribose) polymerase^[1]^[2].

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In Vitro

The extensive cellular accumulation of 8-NH2-ATP has an inhibitory effect on both RNA and DNA synthesis in both glucocorticoid-sensitive and glucocorticoid-resistant myeloma cell lines^[1]^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 35874-49-8
Masse moléculaire 522.20
Formule C₁₀H₁₇N₆O₁₃P₃
SMILES

NC(N([C@]([C@@H]([C@@H]1O)O)([H])O[C@@H]1CO[P](O[P](O[P](O)(O)=O)(O)=O)(O)=O)C2=NC=N3)=NC2=C3N
Synonyms

8-Aminoadenosine-5'-O-triphosphate
Structure Classification
- Others
Initial Source
- Endogenous metabolite
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Nancy L Krett, et al. 8-amino-adenosine is a potential therapeutic agent for multiple myeloma. Mol Cancer Ther. 2004 Nov;3(11):1411-20. [Content Brief]

[2]. Yuji Matsuzaki, et al. ATP-association to intrabacterial nanotransportation system in Vibrio cholera. Med Mol Morphol. 2015 Dec;48(4):225-34. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Activité biologique
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Pureté et documentation
Références

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8-NH2-ATP

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