1. Cell Cycle/DNA Damage
    Epigenetics
  2. HDAC

Citarinostat (Synonyms: ACY241)

Cat. No.: HY-15994 Purity: 99.06%
Handling Instructions

Citarinostat is a HDAC6 specific inhibitor, with IC50 of 4 nM and 76 nM for HDAC6 and HDAC3, respectively.

For research use only. We do not sell to patients.

Citarinostat Chemical Structure

Citarinostat Chemical Structure

CAS No. : 1316215-12-9

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 154 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
5 mg USD 140 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
10 mg USD 220 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
50 mg USD 810 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

Citarinostat is a HDAC6 specific inhibitor, with IC50 of 4 nM and 76 nM for HDAC6 and HDAC3, respectively. IC50 value: 4 nM (HDAC6), 76 nM (HDAC3) Target: HDAC The detailed information please refer to WO2015061684A1 and 2015054197A1.

IC50 & Target[1]

HDAC6

2.6 nM (IC50)

HDAC1

35 nM (IC50)

HDAC2

45 nM (IC50)

HDAC3

46 nM (IC50)

HDAC8

137 nM (IC50)

HDAC7

7300 nM (IC50)

Clinical Trial
Solvent & Solubility
In Vitro: 

DMSO : ≥ 30 mg/mL (64.11 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1370 mL 10.6849 mL 21.3698 mL
5 mM 0.4274 mL 2.1370 mL 4.2740 mL
10 mM 0.2137 mL 1.0685 mL 2.1370 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

467.95

Formula

C₂₄H₂₆ClN₅O₃

CAS No.

1316215-12-9

SMILES

O=C(C1=CN=C(N(C2=CC=CC=C2Cl)C3=CC=CC=C3)N=C1)NCCCCCCC(NO)=O

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Purity: 99.06%

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Citarinostat
Cat. No.:
HY-15994
Quantity:

Citarinostat

Cat. No.: HY-15994