1. Neuronal Signaling Membrane Transporter/Ion Channel Others
  2. Calcium Channel Biochemical Assay Reagents
  3. Coelenterazine h

Coelenterazine h  (Synonyms: 2-Deoxycoelenterazine; CLZN-h)

Cat. No.: HY-D1024 Purity: 98.02%
SDS COA Handling Instructions

Coelenterazine h (2-Deoxycoelenterazine), a coelenterazine derivative, is a luminescent substrate for RLuc8. Coelenterazine h is more sensitive to Ca2+, thus providing a valuable tool for measuring small changes in Ca2+ concentrations.

For research use only. We do not sell to patients.

Coelenterazine h Chemical Structure

Coelenterazine h Chemical Structure

CAS No. : 50909-86-9

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Based on 2 publication(s) in Google Scholar

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Description

Coelenterazine h (2-Deoxycoelenterazine), a coelenterazine derivative, is a luminescent substrate for RLuc8. Coelenterazine h is more sensitive to Ca2+, thus providing a valuable tool for measuring small changes in Ca2+ concentrations[1][2][3][4].

In Vitro

Coelenterazine h (1-10 μM) can be used as the luminescent substrate for RLuc8[4].
In the measurements of Ca2+ binding kinetics of BRAC, emission intensity of Venus (530 nm) from BRAC are monitored at 1 kHz just after rapid mixing of 5 nM BRAC protein with 20 μM coelenterazine-h in various concentration of Ca2+ buffer[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

407.46

Formula

C26H21N3O2

CAS No.
Appearance

Solid

Color

Yellow to brown

SMILES

OC(C=C1)=CC=C1C2=CN(C(C(CC3=CC=CC=C3)=N4)=O)C4=C(N2)CC5=CC=CC=C5

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture and light

*The compound is unstable in solutions, freshly prepared is recommended.

Purity & Documentation

Purity: 98.02%

References
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Product Name:
Coelenterazine h
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HY-D1024
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