1. Metabolic Enzyme/Protease
  2. Fatty Acid Synthase (FAS)
  3. HS80

HS80 

Cat. No.: HY-112522A
Handling Instructions

HS-80 is an enantiomer of Fasnall, which is a selective fatty acid synthase (FASN) inhibitor. HS-80 is able to inhibit the incorporation of tritiated acetate into lipids with an IC50 of 7.13 μM.

For research use only. We do not sell to patients.

HS80 Chemical Structure

HS80 Chemical Structure

CAS No. : 2138838-57-8

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Description

HS-80 is an enantiomer of Fasnall, which is a selective fatty acid synthase (FASN) inhibitor. HS-80 is able to inhibit the incorporation of tritiated acetate into lipids with an IC50 of 7.13 μM.

IC50 & Target

FASN[1]

In Vitro

Fasnall, a thiophenopyrimidine selectively targeting FASN through its co-factor binding sites. Fasnall has anti-proliferative activity and induces apoptosis in breast cancer cells[1].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

338.47

Formula

C₁₉H₂₂N₄S

CAS No.

2138838-57-8

SMILES

CC1=C(C)SC2=NC=NC(N[[email protected]]3CCN(CC4=CC=CC=C4)C3)=C21

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
HS80
Cat. No.:
HY-112522A
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HS80

Cat. No.: HY-112522A