1. Metabolic Enzyme/Protease
  2. Fatty Acid Synthase (FAS)

HS79 

Cat. No.: HY-112522
Handling Instructions

HS-79 is an enantiomer of Fasnall, which is a selective fatty acid synthase (FASN) inhibitor. HS-79 is able to inhibit the incorporation of tritiated acetate into lipids with an IC50 of 1.57 μM.

For research use only. We do not sell to patients.

HS79 Chemical Structure

HS79 Chemical Structure

CAS No. : 2138838-56-7

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  • Biological Activity

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  • References

Description

HS-79 is an enantiomer of Fasnall, which is a selective fatty acid synthase (FASN) inhibitor. HS-79 is able to inhibit the incorporation of tritiated acetate into lipids with an IC50 of 1.57 μM.

IC50 & Target

FASN[1]

In Vitro

Fasnall, a thiophenopyrimidine selectively targeting FASN through its co-factor binding sites. Fasnall has anti-proliferative activity and induces apoptosis in breast cancer cells[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9545 mL 14.7724 mL 29.5447 mL
5 mM 0.5909 mL 2.9545 mL 5.9089 mL
10 mM 0.2954 mL 1.4772 mL 2.9545 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

338.47

Formula

C₁₉H₂₂N₄S

CAS No.

2138838-56-7

SMILES

CC1=C(C)SC2=NC=NC(N[[email protected]@H]3CCN(CC4=CC=CC=C4)C3)=C21

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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This equation is commonly abbreviated as: C1V1 = C2V2

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Product Name:
HS79
Cat. No.:
HY-112522
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HS79

Cat. No.: HY-112522