272 Results for "

Methionine

" in MedChemExpress (MCE) Product Catalog:
Products (272)

272 Results for "Methionine" in MCE Product Catalog:

101
3-TYP
3-TYP
0 Images
101 Publications Verification
Cat. No.: HY-108331
CAS No.: 120241-79-4
Purity:  99.96%
Target:  

Sirtuin Methionine Adenosyltransferase (MAT) Indoleamine 2,3-Dioxygenase (IDO)

Research Areas:  

Cancer

3-TYP is an inhibitor of SIRT3 (IC50of 38 μM) and an inhibitor of Methionine Adenosyltransferase (MAT) 2 and Indoleamine 2,3-Dioxygenase (IDO). There may be many off-target sites for 3-TYP that need to be examined, such as NAD-dependent enzymes, including dehydrogenases .
22
S-Adenosyl-L-methionine
S-Adenosyl-L-methionine
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22 Cited Publications
Cat. No.: HY-B0617
CAS No.: 29908-03-0
Synonyms: S-Adenosyl Methionine; Ademetionine; AdoMet
Category:  

Human Gut Microbiota Metabolites Natural Products Microorganisms Neurological Disease Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:  

Endogenous Metabolite Apoptosis

S-Adenosyl-L-methionine (S-Adenosyl methionine) is an orally active methyl group donor. S-Adenosyl-L-methionine is a dietary supplement with potent antidepressant effects. S-Adenosyl-L-methionine also has anti‑proliferative, pro‑apoptotic and anti‑metastatic roles in cancers. S-Adenosyl-L-methionine has the potential for, cancer, liver disease and osteoarthritis research .
21
S-Adenosyl-L-methionine disulfate tosylate
S-Adenosyl-L-methionine disulfate tosylate
0 Images
21 Cited Publications
Cat. No.: HY-W017770
CAS No.: 97540-22-2
Synonyms: Ademetionine disulfate tosylate; S-Adenosyl Methionine disulfate tosylate; AdoMet disulfate tosylate
Category:  

Ketones, Aldehydes, Acids Endogenous metabolite

Target:  

Endogenous Metabolite Apoptosis

S-Adenosyl-L-methionine (Ademetionine) disulfate tosylate is the disulfate tosylate form of S-Adenosyl-L-methionine (HY-B0617). S-Adenosyl-L-methionine disulfate tosylate is an orally active methyl group donor. S-Adenosyl-L-methionine disulfate tosylate is a dietary supplement with potent antidepressant effects. S-Adenosyl-L-methionine disulfate tosylate also has anti‑proliferative, pro‑apoptotic and anti‑metastatic roles in cancers. S-Adenosyl-L-methionine disulfate tosylate has the potential for, cancer, liver disease and osteoarthritis research .
20
S-Adenosyl-L-methionine tosylate
S-Adenosyl-L-methionine tosylate
0 Images
20 Cited Publications
Cat. No.: HY-B0617A
CAS No.: 52248-03-0
Synonyms: S-Adenosyl Methionine tosylate; Ademetionine tosylate; AdoMet tosylate
Category:  

Natural Products Neurological Disease Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:  

Endogenous Metabolite Apoptosis

S-Adenosyl-L-methionine (S-Adenosyl methionine) tosylate is an orally active methyl group donor. S-Adenosyl-L-methionine tosylate is a dietary supplement with potent antidepressant effects. S-Adenosyl-L-methionine tosylate also has anti‑proliferative, pro‑apoptotic and anti‑metastatic roles in cancers. S-Adenosyl-L-methionine tosylate has the potential for, cancer, liver disease and osteoarthritis research .
19
GSK3368715
GSK3368715
0 Images
19 Cited Publications
Cat. No.: HY-128717
CAS No.: 1629013-22-4
Purity:  99.19%
Synonyms: EPZ019997
Target:  

Histone Methyltransferase

Research Areas:  

Cancer

GSK3368715 (EPZ019997) is an orally active, reversible, and S-adenosyl-L-methionine (SAM) uncompetitive type I protein arginine methyltransferases (PRMTs) inhibitor (IC50=3.1 nM (PRMT1), 48 nM (PRMT3), 1148 nM (PRMT4), 5.7 nM (PRMT6), 1.7 nM (PRMT8)). GSK3368715 (EPZ019997) produces a shift in arginine methylation states, alters exon usage, and has strong anti-cancer activity .
19
GSK3368715 dihydrochloride
GSK3368715 dihydrochloride
0 Images
19 Cited Publications
Cat. No.: HY-128717A
CAS No.: 1628925-77-8
Purity:  99.96%
Synonyms: EPZ019997 dihydrochloride
Target:  

Histone Methyltransferase

Research Areas:  

Cancer

GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) is an orally active, reversible, and S-adenosyl-L-methionine (SAM) uncompetitive type I protein arginine methyltransferases (PRMTs) inhibitor (IC50=3.1 nM (PRMT1), 48 nM (PRMT3), 1148 nM (PRMT4), 5.7 nM (PRMT6), 1.7 nM (PRMT8)). GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) produces a shift in arginine methylation states, alters exon usage, and has strong anti-cancer activity .
18
S-Adenosyl-L-methionine iodide
S-Adenosyl-L-methionine iodide
0 Images
18 Cited Publications
Cat. No.: HY-14614D
CAS No.: 3493-13-8
Synonyms: S-Adenosyl Methionine iodide; Ademetionine iodide; AdoMet iodide
Category:  

Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite Apoptosis

S-Adenosyl-L-methionine (S-Adenosyl methionine) iodide is an orally active methyl group donor. S-Adenosyl-L-methionine iodide is a dietary supplement with potent antidepressant effects. S-Adenosyl-L-methionine iodide also has anti‑proliferative, pro‑apoptotic and anti‑metastatic roles in cancers. S-Adenosyl-L-methionine iodide has the potential for, cancer, liver disease and osteoarthritis research .
18
PF-9366
PF-9366
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18 Cited Publications
Cat. No.: HY-107778
CAS No.: 72882-78-1
Purity:  99.94%
Target:  

Methionine Adenosyltransferase (MAT)

Research Areas:  

Cancer

PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor, with an IC50 of 420 nM and a Kd of 170 nM.
11
Selenomethionine
Selenomethionine
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11 Cited Publications
Cat. No.: HY-B1000
CAS No.: 1464-42-2
Synonyms: Seleno-DL-Methionine; DL-SelenoMethionine
Category:  

Microorganisms Disease markers Amino acids Nervous System Disorder Endogenous metabolite Disease Research Fields Cancer

Target:  

Autophagy Keap1-Nrf2

Selenomethionine is a naturally occurring amino acid containing selenium that has oral activity and is a common natural food source. Selenomethionine has antitumor activity .
10
L-Methionine
L-Methionine
0 Images
10 Cited Publications
Cat. No.: HY-N0326
CAS No.: 63-68-3
Category:  

Anti-aging Endocrine diseases Amino acids Endogenous metabolite Research on Agricultural Breeding Agricultural Research Microorganisms Other Diseases Disease markers Nervous System Disorder Disease Research Fields Cardiovascular System Disorder

Target:  

Environmental Pollutants Endogenous Metabolite Apoptosis Keap1-Nrf2

L-Methionine is an L-isomer of orally active Methionine, an essential amino acid. Methionine is a strong liver antidote that acts as a liver protector. L-Methionine can inhibit cell proliferation and induce cell apoptosis. L-Methionine has antitumor and antioxidant activity .
10
Cycloleucine
Cycloleucine
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10 Cited Publications
Cat. No.: HY-30008
CAS No.: 52-52-8
Target:  

iGluR

Research Areas:  

Infection Neurological Disease Metabolic Disease Cancer

Cycloleucine is a specific inhibitor of S-adenosyl-methionine mediated methylation. Cycloleucine is antagonist of NMDA receptor associated glycine receptor, with a Ki of 600 μM. Cycloleucine is also a competitive inhibitor of ATP: L-methionine-S-adenosyl transferase in vitro. Cycloleucine has anxiolytic and cytostatic effects .
9
S-Adenosyl-L-methionine chloride dihydrochloride
S-Adenosyl-L-methionine chloride dihydrochloride
0 Images
9 Cited Publications
Cat. No.: HY-14614A
CAS No.: 86867-01-8
Purity:  ≥75.0%
Synonyms: S-Adenosyl Methionine chloride dihydrochloride; Ademetionine chloride dihydrochloride; AdoMet chloride dihydrochloride
Target:  

Endogenous Metabolite Apoptosis

Research Areas:  

Neurological Disease Inflammation/Immunology Cancer

S-Adenosyl-L-methionine (S-Adenosyl methionine) chloride dihydrochloride is an orally active methyl group donor. S-Adenosyl-L-methionine chloride dihydrochloride is a dietary supplement with potent antidepressant effects. S-Adenosyl-L-methionine chloride dihydrochloride also has anti‑proliferative, pro‑apoptotic and anti‑metastatic roles in cancers. S-Adenosyl-L-methionine chloride dihydrochloride has the potential for, cancer, liver disease and osteoarthritis research .
9
FIDAS-5
FIDAS-5
0 Images
9 Cited Publications
Cat. No.: HY-136144
CAS No.: 1391934-98-7
Purity:  98.46%
Target:  

Methionine Adenosyltransferase (MAT)

Research Areas:  

Cancer

FIDAS-5 is a potent and orally active methionine S-adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM. FIDAS-5 effectively competes against S-adenosylmethionine (SAM) for MAT2A binding. FIDAS-5 has anticancer activities .
9
Calcium N5-methyltetrahydrofolate
Calcium N5-methyltetrahydrofolate
0 Images
9 Cited Publications
Cat. No.: HY-17557
CAS No.: 26560-38-3
Synonyms: NSC173328; 5-Methyl THF calcium
Target:  

Drug Derivative

Research Areas:  

Cardiovascular Disease Neurological Disease Metabolic Disease Cancer

Calcium N5-methyltetrahydrofolate (NSC173328; 5-Methyl THF (calcium)), Levomefolic acid (HY-14781) derivative, is a folic acid supplement. Calcium N5-methyltetrahydrofolate can be used for the research of neural tube defects, infertility, non-hodgkin's lymphoma, endometriosis .
7
L-Homocysteine
L-Homocysteine
0 Images
7 Cited Publications
Cat. No.: HY-W010347
CAS No.: 6027-13-0
Category:  

Human Gut Microbiota Metabolites Microorganisms Anti-aging Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:  

Endogenous Metabolite Cathepsin

L-Homocysteine, an amino acid, is a homocysteine that has L configuration. Homocysteine is an essential intermediate in normal mammalian metabolism of methionine. L-Homocysteine induces upregulation of Cathepsin V that mediates vascular endothelial inflammation in hyperhomocysteinaemia .
6
L-Methionine-DL-sulfoximine
L-Methionine-DL-sulfoximine
0 Images
6 Cited Publications
Cat. No.: HY-B1692
CAS No.: 15985-39-4
Synonyms: MSX; MSO
Target:  

Glutaminase

Research Areas:  

Neurological Disease

L-Methionine-DL-sulfoximine (MSX; MSO), a highly specific and irreversible inhibitor of Glutamine synthetase (GS), is also a potent convulsant which metabolically and morphologically primarily affects astroglia. L-Methionine-DL-sulfoximine has been employed to inhibit the Gln-dependent ammonia-stimulated neuronal toxicity in vitro, potentiating Gln deficit-dependent depression. L-Methionine-DL-sulfoximine tremendously increases the rate of release of fixed nitrogen in cyanobacteria. L-Methionine-DL-sulfoximine is a promising candidate for research in biofertilizers and convulsive seizures (CS) .
6
Methionine
Methionine
0 Images
6 Cited Publications
Cat. No.: HY-13694
CAS No.: 348-67-4
Purity:  99.86%
Synonyms: MRX-1024; D-Methionine
Category:  

Human Gut Microbiota Metabolites Neurological Disease Amino acids Endogenous metabolite Disease Research Fields Cancer

Target:  

GABA Receptor Endogenous Metabolite

Methionine (MRX-1024; D-Methionine) is an effective chemoprotective agent which can also inhibit the neuronal activity through GABAA receptor activation.
6
Mitoguazone
Mitoguazone
0 Images
6 Cited Publications
Cat. No.: HY-106634
CAS No.: 459-86-9
Purity:  99.33%
Synonyms: Methylglyoxal-bis(guanylhydrazone); MGBG; Methyl-GAG
Target:  

HIV Apoptosis

Research Areas:  

Infection Cancer

Mitoguazone (Methylglyoxal-bis(guanylhydrazone)) is a synthetic polycarbonyl derivative with potent antineoplastic activity. Mitoguazone is a brain-penetrant and competitive S-adenosyl-methionine decarboxylase (SAMDC) inhibitor that disrupts polyamine biosynthesis. Mitoguazone induces cell apoptosis. Mitoguazone inhibits HIV DNA integration into the cellular DNA in both monocytes and macrophages. Mitoguazone has the potential for acute leukemia, Hodgkin's and non-Hodgkin's lymphoma treatment .
4
Tyr-Gly-Gly-Phe-Met-OH
Tyr-Gly-Gly-Phe-Met-OH
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4 Cited Publications
Cat. No.: HY-P0073
CAS No.: 58569-55-4
Synonyms: Met-Enkephalin; Methionine enkephalin; Metenkefalin
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease Cancer

Tyr-Gly-Gly-Phe-Met-OH regulates human immune function and inhibits tumor growth via binding to the opioid receptor.
4
S-Adenosyl-L-methionine-d3 methylbenzenesulfonate
S-Adenosyl-L-methionine-d3 methylbenzenesulfonate
0 Images
4 Cited Publications
Cat. No.: HY-150964S
Synonyms: S-Adenosyl Methionine-d3 methylbenzenesulfonate; Ademetionine-d3 methylbenzenesulfonate; AdoMet-d3 methylbenzenesulfonate
S-Adenosyl-L-methionine-d3 (S-Adenosyl methionine-d3) methylbenzenesulfonate is the deuterium labeled S-Adenosyl-L-methionine methylbenzenesulfonate . S-Adenosyl-L-methionine (S-Adenosyl methionine) is an orally active methyl group donor. S-Adenosyl-L-methionine is a dietary supplement with potent antidepressant effects. S-Adenosyl-L-methionine also has anti‑proliferative, pro‑apoptotic and anti‑metastatic roles in cancers. S-Adenosyl-L-methionine has the potential for, cancer, liver disease and osteoarthritis research .
Assay Types