Borago officinalis L.
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Borago officinalis L. (4)
- Formula: C23H31NO8
- Molecular Weight: 449.49
Thesinine-4'-O-β-D-glucoside is a glycosylated plant pyrrolizidine alkaloid isolated from the seeds of Borago officinalis. Thesinine-4'-O-β-D-glucoside is present in dried seeds at an approximate content of 0.5%.
- Formula: C17H21NO3
- Molecular Weight: 287.35
Thesinine is a saturated pyrrolizidine alkaloid and the primary alkaloid found in the seeds and flowers of Borago officinalis. Thesinine binds to AKT1, MAPK3, MMP9, and MAPK14 proteins as predicted by in silico analysis. Thesinine is applicable to research related to skin aging
- Formula: C19H34O9
- Molecular Weight: 406.47
Actinidioionoside (Compound 2) is a megastigmane glucoside compound found in Borago officinalis L. Actinidioionoside has DPPH free radical scavenging activity (IC50: 41.3 μM). Actinidioionoside has no significant cytotoxicity against A549 human lung cancer cells (IC50 > 100 μM). Actinidioionoside can be used in antioxidant studies.
