Centaurea cyanus L.
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Centaurea cyanus L. (1)
Linichlorin A
Cat. No.: HY-126757
CAS No.: 62462-98-0
- Formula: C19H23ClO6
- Molecular Weight: 382.84
Linichlorin A is a p27Kip1 ubiquitination inhibitor that blocks p27Kip1 degradation by inhibiting the Skp2-Cks1–p27Kip1 interaction. Linichlorin A shows selective antiproliferative activity against tumor cells. Linichlorin A induces apoptosis in leukemia cells via cytochrome c release, caspase activation and PARP cleavage. Linichlorin A can be used in the study of leukemia, melanoma, cervical cancer and breast cancer.
