Cissampelos pareira
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Cissampelos pareira (2)
Cycleanine
- Formula: C38H42N2O6
- Molecular Weight: 622.75
Magnocurarine
- Formula: C19H24NO3
- Molecular Weight: 314.40
Magnocurarine is a neuromuscular junction blocker that inhibits muscle contraction by functionally blocking signal transmission without directly damaging nerve or muscle tissues. In frog, mouse and rabbit models, Magnocurarine exerts a dose-dependent paralytic effect, which progresses gradually from limb weakness and loss of righting reflex to respiratory depression and even cardiac arrest. Although high doses cause complete cessation of movement, Magnocurarine does not affect the spinal multineuronal reflex in frogs. Magnocurarine exhibits biological activity similar to that of tubocurarine (HY-125901) in various animal models.
