- Natural Products
- Plants
- Gnetaceae
- Gnetum montanum Markgr.
Gnetum montanum Markgr.
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Gnetum montanum Markgr. (4)
- Formula: C14H12O4
- Molecular Weight: 244.24
Gnetol is a phenolic compound isolated from the root of Gnetum montanum . Gnetol potently inhibits COX-1 (IC50 of 0.78 μM) and HDAC. Gnetol is a potent tyrosinase inhibitor with an IC50 of 4.5 μM for murine tyrosinase and suppresses melanin biosynthesis. Gnetol has antioxidant, antiproliferative, anticancer and hepatoprotective activity. Gnetol also possesses concentration-dependent α-Amylase, α-glucosidase, and adipogenesis activities.
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- Formula: C32H32O9
- Molecular Weight: 560.59
Gnemontanin F is a natural phenolic compound.
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- Formula: C30H26O8
- Molecular Weight: 514.52
Bisisorhapontigenin A is a dimer of isorhapontigenin. Bisisorhapontigenin A exhibits antagonistic activity against LTD4 and can be used for research on anti-inflammatory effects.
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- Formula: C42H32O11
- Molecular Weight: 712.70
Gnetumontanin B is a stilbenoid that can be found in Gnetum montanum f. megalocarpum. Gnetumontanin B inhibits TNF-α production with an IC50 value of 1.49 µM.
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