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  4. Gnetaceae

Gnetaceae

 

Gnetaceae (17):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N2593
    Isorhapontigenin 32507-66-7 99.82%
    Isorhapontigenin is an orally active dietary polyphenol. Isorhapontigenin acts as a potent antioxidant that reduces the production of reactive oxygen species (ROS). Isorhapontigenin promotes the binding of JUN to the AP-1 site on the SESN2 promoter, induces SESN2 transcription, triggers MAPK8-dependent JUN activation, and upregulates the expression of PPAR-α, PGC-1α and CPT-1A to facilitate fatty acid oxidation. Isorhapontigenin induces autophagy, apoptosis and preadipocyte differentiation; it inhibits tumor growth, cell invasion, NF-κB transcriptional activity, the PI3K/Akt signaling pathway, STAT1 phosphorylation and MMP-2 expression. Isorhapontigenin alleviates oxidative stress, inflammatory cytokine release and triglyceride accumulation; it increases intracellular ATP levels and promotes Nrf2 nuclear translocation. Isorhapontigenin improves insulin sensitivity in adipose tissue and glucose tolerance, and reduces postprandial blood glucose, insulin and free fatty acid levels. Isorhapontigenin is applicable to research on bladder cancer, liver injury, chronic obstructive pulmonary disease, acute lung injury and type 2 diabetes.
    Isorhapontigenin
  • HY-126052
    Gnetol 86361-55-9 99.86%
    Gnetol is a phenolic compound isolated from the root of Gnetum montanum . Gnetol potently inhibits COX-1 (IC50 of 0.78 μM) and HDAC. Gnetol is a potent tyrosinase inhibitor with an IC50 of 4.5 μM for murine tyrosinase and suppresses melanin biosynthesis. Gnetol has antioxidant, antiproliferative, anticancer and hepatoprotective activity. Gnetol also possesses concentration-dependent α-Amylase, α-glucosidase, and adipogenesis activities.
    Gnetol
  • HY-N17029
    Gnetuhainin O 337464-95-6
    Gnetuhainin O is a natural phenolic compound.
    Gnetuhainin O
  • HY-N17024
    Gnetuhainin N 337464-99-0
    Gnetuhainin N is a natural phenolic compound.
    Gnetuhainin N
  • HY-N13757
    Gnetifolin A 137476-72-3
    Gnetifolin A is a natural phenolic compound.
    Gnetifolin A
  • HY-N16994
    Gnemontanin F 2210293-19-7
    Gnemontanin F is a natural phenolic compound.
    Gnemontanin F
  • HY-N16620
    Gnetucleistol F 913529-99-4
    Gnetucleistol F is a stilbenolignan isolated from Gnetum cleistostachyum with anti-inflammatory activity. Gnetucleistol F exhibits potent inhibitory activities on TNF-α and malondialdehyde (MDA) with IC50 values of 10.3 and 6.36 μM, respectively. Gnetucleistol F can be used for anti-inflammatory research.
    Gnetucleistol F
  • HY-N16543
    Bisisorhapontigenin A 332381-09-6
    Bisisorhapontigenin A is a dimer of isorhapontigenin. Bisisorhapontigenin A exhibits antagonistic activity against LTD4 and can be used for research on anti-inflammatory effects.
    Bisisorhapontigenin A
  • HY-N16581
    Gnetucleistol C 864763-61-1
    Gnetucleistol C is a type of dihydroquercetin compound, which can be found in the plants Gnetum cleistostachyum and Gnetum microcarpum.
    Gnetucleistol C
  • HY-N15749
    Gnetin D 84870-53-1
    Gnetin D is a stilbenoid.
    Gnetin D
  • HY-N2593R
    Isorhapontigenin (Standard) 32507-66-7
    Isorhapontigenin (Standard) is the analytical standard of Isorhapontigenin (HY-N2593). This product is intended for research and analytical applications. Isorhapontigenin is an orally active dietary polyphenol. Isorhapontigenin acts as a potent antioxidant that reduces the production of reactive oxygen species (ROS). Isorhapontigenin promotes the binding of JUN to the AP-1 site on the SESN2 promoter, induces SESN2 transcription, triggers MAPK8-dependent JUN activation, and upregulates the expression of PPAR-α, PGC-1α and CPT-1A to facilitate fatty acid oxidation. Isorhapontigenin induces autophagy, apoptosis and preadipocyte differentiation; it inhibits tumor growth, cell invasion, NF-κB transcriptional activity, the PI3K/Akt signaling pathway, STAT1 phosphorylation and MMP-2 expression. Isorhapontigenin alleviates oxidative stress, inflammatory cytokine release and triglyceride accumulation; it increases intracellular ATP levels and promotes Nrf2 nuclear translocation. Isorhapontigenin improves insulin sensitivity in adipose tissue and glucose tolerance, and reduces postprandial blood glucose, insulin and free fatty acid levels. Isorhapontigenin is applicable to research on bladder cancer, liver injury, chronic obstructive pulmonary disease, acute lung injury and type 2 diabetes.
    Isorhapontigenin (Standard)
  • HY-N9867
    Gnetifolin E 140671-07-4
    Gnetifolin E is a resveratrol trimer derivative that can be isolated from Gnetum brunonianum. Gnetifolin E has anti-inflammatory activity, and inhibits TNF-α.
    Gnetifolin E
  • HY-N10835
    Gnetumontanin B 809237-87-4
    Gnetumontanin B is a stilbenoid that can be found in Gnetum montanum f. megalocarpum. Gnetumontanin B inhibits TNF-α production with an IC50 value of 1.49 µM.
    Gnetumontanin B
  • HY-N7524
    Gnetulin 152340-24-4
    Gnetulin is isolated from the lianas of Gnetum cleistostachyum C. Y. Cheng.
    Gnetulin
  • HY-N13409
    Gnetofuran B 526214-79-9
    Gnetofuran B is a natural product.
    Gnetofuran B
  • HY-N13642
    Gneafricanin F 477561-12-9
    Gneafricanin F is a natural product.
    Gneafricanin F
  • HY-N8304
    Shegansu B 291535-65-4
    Shegansu B is an inhibitor of IL-1β. Shegansu B 6 inhibits IL-1β expression on LPS-induced THP-1 cells with 64.74% inhibition. Shegansu B has anti-inflammatory activity.
    Shegansu B