Juglans sigillata Dode
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Juglans sigillata Dode (3)
- Formula: C10H6O4
- Molecular Weight: 190.15
Naphthazarin (DHNQ) is a microtubule depolymerizing agent. Naphthazarin can improve motor function and reduce neuroinflammation in mouse models of Parkinson's disease. Naphthazarin can induce tumor cell apoptosis, autophagy, and cell cycle arrest. Naphthazarin can also induce erythrocyte apoptosis. Naphthazarin can be used in the research of tumors and neurodegenerative diseases.
- Formula: C10H6O4
- Molecular Weight: 190.15
Naphthazarin (DHNQ) is a naturally occurring compound. Naphthazarin is effective by various cellular mechanisms including oxidative stress, activation of mitochondrial apoptosis-inducing factor (AIF), depolymerization of microtubules, interference with lysosomal function and p53-dependent p21 activation. Naphthazarin triggers apoptosis and has anti-tumor effects.
- Formula: C10H10O3
- Molecular Weight: 178.18
(3S,4S)-3,4-Dihydro-3,4-dihydroxynaphthalen-1(2H)-one (compound 9) is α-tetralone galloylglucoside that can be isolated from Juglans sigillata.
