Sinopodophyllum hexandrum (Royle) Ying

Etoposide (VP-16; VP-16-213) is an anti-cancer chemotherapy agent. Etoposide inhibits topoisomerase II, thus stopping DNA replication. Etoposide induces cell cycle arrest, apoptosis and autophagy.

Etoposide (Standard) is the analytical standard of Etoposide. This product is intended for research and analytical applications. Etoposide (VP-16; VP-16-213) is an anti-cancer chemotherapy agent. Etoposide inhibits topoisomerase II, thus stopping DNA replication. Etoposide induces cell cycle arrest, apoptosis and autophagy.

4'-Demethylpodophyllotoxin is an aryltetralin lignin contained in the root of Podophyllum hexandrum and P. peltatum. 4'-Demethylpodophyllotoxin exhibits cytotoxic potential in diverse cancer cell lines.

4-Demethyldeoxypodophyllotoxin is an aryltetralin lignan that can be found in Podophyllum peltatum.

4'-Demethyldehydropodophyllotoxin is an aryltetralin lignan that can be isolated from leaves of Podophyllum hexandrum. 4'-Demethyldehydropodophyllotoxin exhibits some cytotoxic and antitumour activity.

Picropodophyllone, an aryltetralin lignan, is isolated from leaves of Podophyllum hexandrum, and has antifungal activities.

8,2'-Diprenylquercetin 3-methyl ether is isolated from Sinopodophyllum hexandrum (Royle) Ying (Sinopodophylli Fructus). 8,2'-Diprenylquercetin 3-methyl ether is cytotoxic to MDA-231 and T47D breast cancer cell lines.

Sinopodophylline B (compound 2) is a flavonoid glycoside compound that is cytotoxic to breast cancer cells. For example, the IC₅₀ of Sinopodophylline B is 1.5 μM (T47D) and 44.2 μM (MDA-MB-231), respectively.

Picropodophyllin-β-D-glucoside (compound 3) is a podophyllotoxin glucoside isolated from Chinese medicinal plants.

Picropodophyllin-4-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranoside (compound 17) is a lignan isolated from the roots and rhizomes of Podophyllum sinensis.