Sinopodophylline B
Sinopodophylline B (compound 2) is a flavonoid glycoside compound that is cytotoxic to breast cancer cells. For example, the IC50 of Sinopodophylline B is 1.5 μM (T47D) and 44.2 μM (MDA-MB-231), respectively.
For research use only. We do not sell to patients.
- CAS No.: 1369959-47-6
- Formula: C21H20O7
- Molecular Weight:384.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Hep 3B2 | IC50 |
2.39 μM
Compound: 22
|
Cytotoxicity against human Hep3B cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay
Cytotoxicity against human Hep3B cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay
|
[PMID: 36549116] |
| HepG2 | IC50 |
>50 μM
Compound: 22
|
Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay
|
[PMID: 36549116] |
Chemical Information
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CAS No. 1369959-47-6
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Molecular Weight 384.38
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Formula C21H20O7
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SMILES
COC1=C(C2=CC=C(O)C(O)=C2)OC3=C(C/C=C(C)\C)C(O)=CC(O)=C3C1=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)