4'-Demethyldehydropodophyllotoxin
Based on 1 Customer Validation
4'-Demethyldehydropodophyllotoxin is an aryltetralin lignan that can be isolated from leaves of Podophyllum hexandrum. 4'-Demethyldehydropodophyllotoxin exhibits some cytotoxic and antitumour activity.
For research use only. We do not sell to patients.
- Purity : 99.79%
- CAS No.: 117669-31-5
- Formula: C21H16O8
- Molecular Weight:396.35
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
>100 μM
Compound: 11
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Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
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[PMID: 21570846] |
| KB | ED50 |
2.2 μg/mL
Compound: 7
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Cytotoxicity against human KB cells
Cytotoxicity against human KB cells
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[PMID: 2849640] |
| KB | IC50 |
84.7 μM
Compound: 11
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Cytotoxicity against human KB cells after 72 hrs by MTT assay
Cytotoxicity against human KB cells after 72 hrs by MTT assay
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[PMID: 21570846] |
Chemical Information
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CAS No. 117669-31-5
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Appearance Solid
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Molecular Weight 396.35
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Formula C21H16O8
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Color White to off-white
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SMILES
O=C1OCC2=C(C3=C(C(C4=CC(OC)=C(C(OC)=C4)O)=C12)C=C5OCOC5=C3)O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
In Vitro:
DMSO : 10 mg/mL (25.23 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5230 mL | 12.6151 mL | 25.2302 mL | 63.0756 mL |
| 5 mM | 0.5046 mL | 2.5230 mL | 5.0460 mL | 12.6151 mL | |
| 10 mM | 0.2523 mL | 1.2615 mL | 2.5230 mL | 6.3076 mL | |
| 15 mM | 0.1682 mL | 0.8410 mL | 1.6820 mL | 4.2050 mL | |
| 20 mM | 0.1262 mL | 0.6308 mL | 1.2615 mL | 3.1538 mL | |
| 25 mM | 0.1009 mL | 0.5046 mL | 1.0092 mL | 2.5230 mL |
4'-Demethyldehydropodophyllotoxin Related Classifications
HY-N9318 Related Classifications
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