Spiraea japonica

Spiraea japonica (10):

Cat. No.	Product Name	CAS No.	Purity	Chemical Structure

Spiramide	510-74-7	99.23%
Spiramide (AMI-193) is a potent and selective antagonist of 5-HT₂ and dopamine D2 receptor, with K_is of 2 nM and 3 nM, respectively. Spiramide has >2000-fold selectivity for 5-HT₂ versus 5-HT_1C (K_i=4300 nM) receptors. Spiramide exhibits antipsychotic activity.

Spiradine G	21040-66-4
Spiradine G is a natural alkaloid.

Spirasine III	112496-48-7
Spirasine III (9-Hydroxyspiredine) is a natural alkaloid.

Spiredine	60062-45-5
Spiredine is a natural alkaloid.

Spiramine B	114485-96-0
Spiramine B is a natural alkaloid.

Spiratisanin A	1902173-16-3
Spiratisanin A is a natural diterpene.

Spiratisanin C	1902173-22-1
Spiratisanin C is a natural diterpene.

Spiratisanin B	1902173-19-6
Spiratisanin B is an atisane diterpenoid from Spiraea japonica.

Spiradine F	21040-64-2
Spiradine F is a main alkaloidal component of spiraea japonioa L. fil. Spiradine F derivative can inhibit platelet-activating factor (PAF)-induced platelet aggregation.

Spiramine A	114531-28-1
Spiramine A (Spiramine C acetate (ester)) is a diterpene alkaloid with antitumor and antimicrobial activity. Spiramine A inhibits PAF-induced rabbit platelet aggregation in a concentration-dependent manner, with an IC₅₀ vallue of 6.7 μM.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

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