1. GPCR/G Protein
    Neuronal Signaling
  2. 5-HT Receptor
  3. Quetiapine

Quetiapine (Synonyms: ICI204636)

Cat. No.: HY-14544 Purity: 99.97%
Handling Instructions

Quetiapine (ICI204636) is an atypical antipsychotic used in the treatment of schizophrenia, bipolar I mania, bipolar II depression, bipolar I depression.

For research use only. We do not sell to patients.

Quetiapine Chemical Structure

Quetiapine Chemical Structure

CAS No. : 111974-69-7

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Estimated Time of Arrival: December 31
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100 mg USD 144 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Quetiapine (ICI204636) is an atypical antipsychotic used in the treatment of schizophrenia, bipolar I mania, bipolar II depression, bipolar I depression.

IC50 & Target

5-HT Receptor[1].

In Vitro

Quetiapine (ICI204636) is indicated for the treatment of schizophrenia as well as for the treatment of acute manic episodes associated with bipolar I disorder. The antipsychotic effect of quetiapine is thought by some to be mediated through antagonist activity at dopamine and serotonin receptors. Specifically the D1 and D2 dopamine, the alpha 1 adrenoreceptor and alpha 2 adrenoreceptor, and 5-HT1A and 5-HT2 serotonin receptor subtypes are antagonized. Quetiapine (ICI204636) also has an antagonistic effect on the histamine H1 receptor.

Clinical Trial
Molecular Weight

383.51

Formula

C₂₁H₂₅N₃O₂S

CAS No.

111974-69-7

SMILES

OCCOCCN(CC1)CCN1C2=NC3=CC=CC=C3SC4=C2C=CC=C4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Pure form -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : < 0.1 mg/mL (insoluble)

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KeyWords:

Quetiapine | ICI204636 | ICI 204636 | ICI-204636 | 5-HT Receptor | Serotonin Receptor | 5-hydroxytryptamine Receptor | Inhibitor | inhibitor | inhibit

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Quetiapine
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