1. Membrane Transporter/Ion Channel
  2. Na+/H+ Exchanger (NHE)
  3. Rimeporide hydrochloride

Rimeporide hydrochloride  (Synonyms: EMD-87580 hydrochloride)

Cat. No.: HY-19273A
Handling Instructions

Rimeporide hydrochloride (EMD-87580 hydrochloride) is a potent and selective inhibitor of the Na+/H+ exchanger (NHE-1).

For research use only. We do not sell to patients.

Rimeporide hydrochloride Chemical Structure

Rimeporide hydrochloride Chemical Structure

CAS No. : 187870-95-7

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Top Publications Citing Use of Products

1 Publications Citing Use of MCE Rimeporide hydrochloride

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Rimeporide hydrochloride (EMD-87580 hydrochloride) is a potent and selective inhibitor of the Na+/H+ exchanger (NHE-1).

IC50 & Target

NHE1[1]

In Vitro

Blocking NHE-1 activity has been shown to decrease intracellular Na+ and Ca2+ overload and pH and Rimeporide (EMD-87580) represents a new therapeutic option for duchenne muscular dystrophy (DMD). Rimeporide (EMD-87580) is expected to act as a muscle-sparing agent and its mode of action means that it is mutation independent[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

369.84

Formula

C11H16ClN3O5S2

CAS No.
SMILES

O=C(NC(N)=N)C1=CC(S(=O)(C)=O)=C(S(=O)(C)=O)C=C1C.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Rimeporide hydrochloride Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Rimeporide hydrochloride
Cat. No.:
HY-19273A
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