1. GPCR/G Protein
    Neuronal Signaling
  2. Opioid Receptor
  3. SR17018

SR17018 

Cat. No.: HY-111454 Purity: >98.0%
Handling Instructions

SR17018 is an mu-opioid-receptor (MOR) agonist, binding with GTPγS, with an EC50 of 97 nM.

For research use only. We do not sell to patients.

SR17018 Chemical Structure

SR17018 Chemical Structure

CAS No. : 2134602-45-0

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 275 In-stock
Estimated Time of Arrival: December 31
5 mg USD 250 In-stock
Estimated Time of Arrival: December 31
10 mg USD 350 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1100 In-stock
Estimated Time of Arrival: December 31
100 mg USD 1600 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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  • Biological Activity

  • Technical Information

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Description

SR17018 is an mu-opioid-receptor (MOR) agonist, binding with GTPγS, with an EC50 of 97 nM.

IC50 & Target

EC50: 97 nM (MOR)[1]

In Vitro

SR17018 is an mu-opioid-receptor (MOR) agonist, binding with GTPγS, with an EC50 of 97 nM. SR17018 shows no obvious effect on inducing βarrestin2 recruitment to the MOR at below 10 μM. SR17018 promotes signaling through G proteins or βarrestin2[1].

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 6.4 mg/mL (15.58 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4347 mL 12.1737 mL 24.3475 mL
5 mM 0.4869 mL 2.4347 mL 4.8695 mL
10 mM 0.2435 mL 1.2174 mL 2.4347 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

410.72

Formula

C₁₉H₁₈Cl₃N₃O

CAS No.

2134602-45-0

SMILES

O=C1NC2=CC(Cl)=C(Cl)C=C2N1C3CCN(CC4=CC=C(Cl)C=C4)CC3

Shipping

Room temperature in continental US; may vary elsewhere

Purity: >98.0%

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Product Name:
SR17018
Cat. No.:
HY-111454
Quantity:

SR17018

Cat. No.: HY-111454