Sodium laureth sulfate (70% in water)  (Synonyms: Sodium lauryl polyoxyethylene ether sulfate)

Sodium laureth sulfate (70% in water) (Sodium lauryl polyoxyethylene ether sulfate) is an anionic active agent with excellent decontamination, emulsification, dispersion, wetting, antifungal and other properties^[1][2][3][4].

Sodium laureth sulfate (0.1-2.5 mg/mL, 20 min) combined with plasma-activated water (PAW) enhances the inactivation efficiency against S. cerevisiae cells^[2].
Sodium laureth sulfate (0.5 mg/mL, 20 min) combined with PAW causes the formation of holes and wrinkles on the surface of S. cerevisiae cells^[2].
Sodium laureth sulfate (0.01-0.5 mg/mL, 20 min) disrupts the membrane integrity, increases cell membrane permeability of S. cerevisiae cells and ROS generation^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Sodium laureth sulfate (50 mg/kg, mixed in distilled water, a single dose for 7 or 14 days) elevates the activities of lysosomal enzymes such as ACP, P-glucuronidase, LDH, MDH, ALP, AST and ALT in guinea pigs ^[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

(C₂H₄O)nC₁₂H₂₆O₄S.Na

9004-82-4

Oil

Colorless to off-white

CCCCCCCCCCCCOCCOS(=O)(O[Na])=O.[n]

Room temperature in continental US; may vary elsewhere.

Solution, -20°C, 2 years

• [1]. Löffler H, et al. Profile of irritant patch testing with detergents: sodium lauryl sulfate, sodium laureth sulfate and alkyl polyglucoside. Contact Dermatitis. 2003 Jan;48(1):26-32.  [Content Brief]

  [2]. Liu X, et al. Inactivation effects and mechanisms of plasma-activated water combined with sodium laureth sulfate (SLES) against Saccharomyces cerevisiae. Appl Microbiol Biotechnol. 2021 Apr;105(7):2855-2865.  [Content Brief]

  [3]. CASCORBI HF, et al. ACUTE TOXICITY OF INTRAVENOUS SODIUM LAURYL SULFATE. J Pharm Sci. 1963 Aug;52:803-5.  [Content Brief]

  [4]. Mathur AK, et al. Effect of sodium lauryl sulphate and nickel alone and in combination on the skin of guinea pigs. Toxicol Lett. 1988 Sep;42(3):249-56.  [Content Brief]