Cannabinoid Receptor Ligand

Cannabidivarinic acid (CBDVA), the carboxylic acid precursor of Cannabidivarin(CBDV), is a non-psychoactive cannabinoid found in Cannabis with anti-inflammatory properties.

Cannabicitran is a cannabinoid. Cannabicitran can decrease intraocular pressure in rabbits.

CB2R ligand-1 (Compound L14) is a selective Cannabinoid type 2 receptor (CB2R) ligand with a with K_i of 0.16  nM for CB2R over CB1R. CB2R ligand-1 as be used as a tracer for positron emission tomography (PET) imaging of neurodegenerative diseases, inflammation and cancer.

BB-22 is a cannabinoid wih dopamine (DA) stimulant properties. BB-22 shows affinity to CB1 receptors with a K_i value of 0.11 nM and an EC₅₀ value of 2.9 nM.

Δ8-THCB (∆8-Tetrahydrocannabutol) is a structural analog of phytocannabinoids. Δ8-THCB is also an analog of Δ8-tetrahydrocannabinol.

10α-hydroxy-exo-THC is a cannabinoid compound, a metabolite of Δ9-THC, and can be found in cannabis. 10α-hydroxy-exo-THC can serve as an analytical reference standard for cannabinoid compounds .

exo-Tetrahydrocannabivarin (Compound 12) is a Δ^9,11-THC analogue. exo-Tetrahydrocannabivarin weakly binds to cannabinoid receptors (CB) (IC₅₀: 1.4 μM). exo-Tetrahydrocannabivarin is active on both motor and analgesic aspects in mice.

Anti-inflammatory agent 94 (compound 4b) is a potent cannabinoid ligand with K_is of 29 nM and 8 nM against CB2 and CB1. Anti-inflammatory agent 94 can be utilized in inflammation rersearch.