2. Signaling Pathways
  3. Cell Cycle/DNA Damage
  4. Deubiquitinase
  5. Deubiquitinase Ligand

Deubiquitinase Ligand

Deubiquitinase Isoform Comparison

Deubiquitinase Ligands (5):

Cat. No. Product Name Effect Purity
  • HY-143345
    EN523
    		Ligand 99.22%
    EN523 is a OTUB1 recruiter. EN523 targets a non-catalytic allosteric cysteine C23 in the K48-ubiquitin-specific deubiquitinase OTUB1.
  • HY-180826
    USP7 ligand-2
    		Ligand
    USP7 ligand-2 is a target protein ligand that can be used for the synthesis of PROTACs, such as PROTAC USP7 Degrader-2 (HY-180793.
  • HY-W027296
    UBTR008295a
    		Ligand
    UBTR008295a is a USP5 ZnF-UBD binder with a Kd of 80 μM. UBTR008295a interacts with USP5 ZnF-UBD. UBTR008295a is applicable for cancer research.
  • HY-183724
    MS8572
    		Ligand
    MS8572 is a selective OTUB1 covalent ligand. MS8572 covalently modifies the noncatalytic cysteine 23 residue of OTUB1 and does not inhibit OTUB1 deubiquitinase activity. MS8572 can be used for development of deubiquitinase-targeting chimeras for targeted protein stabilization.
  • HY-175934
    MS5105
    		Ligand
    MS5105 is a covalent ligand of the deubiquitinating enzyme OTUB1, which can be used to construct DUBTACs, such as MS8588 (HY-162967).