3060517-63-4
3060517-63-4
Chemical Structure
MS8572
- CAS No.: 3060517-63-4
- Formula:C17H23N3O2S
- Molecular Weight:333.45
InChIKey: HTHCRIXCDJQLDO-SNAWJCMRSA-N
SMILES: CC1=CC=C(S1)C(N2CC3CC(C2)N3C(/C=C/CN(C)C)=O)=O
Biological Activity: MS8572 is a selective OTUB1 covalent ligand. MS8572 covalently modifies the noncatalytic cysteine 23 residue of OTUB1 and does not inhibit OTUB1 deubiquitinase activity. MS8572 can be used for development of deubiquitinase-targeting chimeras for targeted protein stabilization[1].
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MS8572 | MS8572 is a selective OTUB1 covalent ligand. MS8572 covalently modifies the noncatalytic cysteine 23 residue of OTUB1 and does not inhibit OTUB1 deubiquitinase activity. MS8572 can be used for development of deubiquitinase-targeting chimeras for targeted protein stabilization. | |||||||||||||||||||||
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References
Keywords
