2. Signaling Pathways
  3. Epigenetics
  4. Histone Methyltransferase
  5. EZH1 Isoform
  6. EZH1 Inhibitor

EZH1 Inhibitor

EZH1 Inhibitors (5):

Cat. No. Product Name Effect Purity
  • HY-15646
    UNC1999
    		Inhibitor 99.83%
    UNC1999 is a SAM-competitive, potent and selective inhibitor of EZH2/1 with IC50s of <10 nM and 45 nM, repectively.
  • HY-109108A
    Valemetostat tosylate
    		Inhibitor 98.14%
    Valemetostat (DS-3201) tosylate, a first-in-class EZH1/2 dual inhibitor with IC50 values ＜10 nM. Valemetostat tosylate can be used for the research of relapsed/refractory peripheral T-cell lymphoma.
  • HY-109108
    Valemetostat
    		Inhibitor 99.65%
    Valemetostat (DS-3201), a first-in-class EZH1/2 dual inhibitor with IC50 values ＜10 nM. Valemetostat can be used for the research of relapsed/refractory peripheral T-cell lymphoma.
  • HY-144881
    (S)-HH2853
    		Inhibitor
    (S)-HH2853 (compound 200), a PYRIDINO five membered aromatic ring compound, is a potent EZH1/2 dual inhibitor with an IC50 of <100 nM for EZH2_Y641F. (S)-HH2853 has the potential to be used in the research of anti-tumor or autoimmune diseases.
  • HY-145602
    Tulmimetostat
    		Inhibitor
    Tulmimetostat (CPI-0209) is an orally active EZH1/EZH2 inhibitor that targets and inhibits the EZH2 enzyme.Tulmimetostat has antitumor activity and is used in a variety of solid tumor studies.