PROTAC Linkers

PROTAC Linkers Chemicals (5)

PROTAC Linkers 関連製品 (1523):

製品番号	製品名	CAS 番号	純度	構造式

trans-Cyclohexane-p-bis(C-OTs)	134424-54-7
trans-Cyclohexane-p-bis(C-OTs) is the linker that can be used for synthesis of PROTAC degrader dBAZ2 (HY-168448).

Boc-piperidine-oxopiperidin	3078378-93-2
Boc-piperidine-oxopiperidin is a PROTAC linker. Boc-piperidine-oxopiperidin can be used to synthesize PROTAC LYA914 (HY-175455).

DBCO-PEG2-PFP ester	2304558-23-2
DBCO-PEG2-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. DBCO-PEG2-PFP ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Methyl (R)-2-(3-(4-bromobutoxy)isoxazol-5-yl)-3-methylbutanoate
Methyl (R)-2-(3-(4-bromobutoxy)isoxazol-5-yl)-3-methylbutanoate is a PROTAC linker that can be used for the synthesis of PROTACs, such as PROTAC K-Ras Degrader-4 (HY-159788).

Boc-NHCH2-Ph-Py-NH2	3040121-14-7
Boc-NHCH2-Ph-Py-NH2 is the linker for PROTAC molecule XYD190 (HY-161494).

(2-Aminoethyl)carbamic acid	109-58-0
(2-Aminoethyl)carbamic acid is a PROTAC linker that belongs to the PEG class. (2-Aminoethyl)carbamic acid can be used to synthesize QS-57 (HY-169081).

Propargyl-PEG14-OH
Propargyl-PEG14-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG14-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

COOEt-bicyclo[2.2.2]octane-CHO	959958-67-9
PROTAC SMARCA2 degrader-6-Linker is a PROTAC linker that connects the E3 ligase ligand and the SMARCA2 ligand to form PROTAC SMARCA2 degrader-6 (HY-159448).

4-(1,3-Dioxolan-2-yl)phenethyl methanesulfonate	2369046-75-1
4-(1,3-Dioxolan-2-yl)phenethyl methanesulfonate is a PROTAC Linker. 4-(1,3-Dioxolan-2-yl)phenethyl methanesulfonate can be used in the synthesis of PROTAC SMARCA2/4-degrader-27 (HY-162834).

exo-BCN-Fmoc-L-Lysine	1493802-76-8
exo-BCN-Fmoc-L-Lysine is a Click Amino Acid that can be used as a linker in the synthesis of PROTAC molecules. exo-BCN-Fmoc-L-Lysine contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

NH2-PEG-phenol-PEG-COOtBu	2417370-72-8
NH2-PEG-phenol-PEG-COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs, such as PROTAC BRD4 Degrader-14 (HY-138637).

HY-W017440S

Triethylene glycol-d₁₂	140196-13-0
Triethylene glycol-d₁₂ (PROTAC Linker 25-d₁₂) is the deuterium labeled Triethylene glycol (HY-W017440). Triethylene glycol (PROTAC Linker 25) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

2-Azidoethanol-d₄
2-Azidoethanol-d₄ is the deuterium labeled Azido-PEG1 (HY-138461). Azido-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG1 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

(R)-TCO4-PEG7-NH2
(R)-TCO4-PEG7-NH2 is a PROTAC linker and belongs to the PEG class. (R)-TCO4-PEG7-NH2 contains a TCO group that specifically "clicks" with the tetrazine group.

(Methylamino)acetaldehyde	145757-95-5
(Methylamino)acetaldehyde is a linker. (Methylamino)acetaldehyde can be used in the synthesis of PROTACs, such as WZH-17-002 (HY-174315).

7-Azaspiro[3.5]nonane-piperidine-Boc
7-Azaspiro[3.5]nonane-piperidine-Boc is a PROTAC linker. 7-Azaspiro[3.5]nonane-piperidine-Boc can be used to synthesize RP03707 (HY-176134).

m-PEG8-Tos	82217-01-4
Tos-PEG8-m is a derivative of silybin ethers, extracted from patent CN105037337A (compound III-d). Tos-PEG8-m is a PEG-based PROTAC linker can be used in the synthesis of Silymarin (HY-W043277).

Alkyne-pyrazine-O-piperidine-(1-methylcyclopropyl)methanol
Alkyne-pyrazine-O-piperidine-(1-methylcyclopropyl) methanol is a PROTAC linker that can be used in the synthesis of PROTACs, such as PROTAC pan-KRAS degrader-1 (HY-176489).

7-Azaspiro[3.5]nonane-2-ethanol	1370211-12-3
7-Azaspiro[3.5]nonane-2-ethanol is a PROTAC linker can be used in the synthesis of PROTAC, KTX-951 (HY-148290).

HY-W024365R

3-tert-Butyl-4-methoxyphenol (Standard)	88-32-4
3-tert-Butyl-4-methoxyphenol (Standard) is the analytical standard of 3-tert-Butyl-4-methoxyphenol. This product is intended for research and analytical applications. 3-tert-Butyl-4-methoxyphenol is a PROTAC linker, belongs to alkyl/ether class, with insecticidal activity. 3-tert-Butyl-4-methoxyphenol also induced increased activities of glutathione (GSH) S-transferase and epoxide hydrolase in the liver and forestomach tissues of A/HeJ mice, regulating the carcinogen metabolism system.

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