2. Signaling Pathways
  3. Membrane Transporter/Ion Channel
  4. Sodium Channel
  5. Nav1.3 Isoform
  6. Nav1.3 Inhibitor

Nav1.3 Inhibitor

Nav1.3 Inhibitors (6):

Cat. No. Product Name Effect Purity
  • HY-16787
    ICA-121431
    		Inhibitor 98.65%
    ICA-121431 is a nanomolar potent and broad-spectrum voltage-gated sodium channel (Nav) blocker, shows equipotent selectivity for human Nav1.1 and Nav1.3 subtypes with IC50 values of 13 nM and 23 nM, respectively.
  • HY-107405
    TC-N 1752
    		Inhibitor 99.18%
    TC-N 1752 is a potent and orally active inhibitor of Nav1.7, with IC50s of 0.17 μM, 0.3 μM, 0.4 μM, 1.1 μM and 2.2 μM at hNav1.7, hNav1.3, hNav1.4, hNaV1.5 and rNav1.8, respectively.
  • HY-P1218
    Phrixotoxin 3
    		Inhibitor
    Phrixotoxin 3 is a potent blocker of voltage-gated sodium channels, with IC50s of 0.6, 42, 72, 288, 610 nM for NaV1.2, NaV1.3, NaV1.4, NaV1.1 and NaV1.5, respectively.
  • HY-P1220
    Huwentoxin-IV
    		Inhibitor
    Huwentoxin-IV is a potent and selective sodium channel blocker, inhibits neuronal Nav1.7, Nav1.2, Nav1.3 and Nav1.4 with IC50s of 26, 150, 338 and 400 nM, respectively.
  • HY-P1220A
    Huwentoxin-IV TFA
    		Inhibitor
    Huwentoxin-IV TFA is a potent and selective sodium channel blocker, inhibits neuronal Nav1.7, Nav1.2, Nav1.3 and Nav1.4 with IC50s of 26, 150, 338 and 400 nM, respectively.
  • HY-N1847
    3'-Methoxydaidzein
    		Inhibitor
    3'-Methoxydaidzein is a isoflavone and a Sodium Channel inhibitor.