2. Membrane Transporter/Ion Channel
  3. Sodium Channel
  4. 3'-Methoxydaidzein

3'-Methoxydaidzein is a isoflavone and a Sodium Channel inhibitor. 3'-Methoxydaidzein inhibits subtypes NaV1.7, NaV1.8 and NaV1.3 with IC50 of 181 nM, 397 nM, and 505 nM, respectively. 3'-Methoxydaidzein exerts analgesic activity by inhibiting voltage-gated sodium channels.

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3'-Methoxydaidzein Chemical Structure

3'-Methoxydaidzein Chemical Structure

CAS No. : 21913-98-4

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3'-Methoxydaidzein Related Antibodies

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Description

3'-Methoxydaidzein is a isoflavone and a Sodium Channel inhibitor. 3'-Methoxydaidzein inhibits subtypes NaV1.7, NaV1.8 and NaV1.3 with IC50 of 181 nM, 397 nM, and 505 nM, respectively. 3'-Methoxydaidzein exerts analgesic activity by inhibiting voltage-gated sodium channels[1].

IC50 & Target[1]

Nav1.3

505 nM (IC50)

Nav1.7

181 nM (IC50)

Nav1.8

397 nM (IC50)

Molecular Weight

284.26

Formula

C16H12O5
CAS No.
SMILES

O=C1C(C2=CC=C(O)C(OC)=C2)=COC3=CC(O)=CC=C13
Structure Classification
Initial Source
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Purity & Documentation
References
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3'-Methoxydaidzein Related Classifications

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Keywords:

3'-Methoxydaidzein21913-98-4Sodium ChannelNa channelsNa+ channelsInhibitorinhibitorinhibit

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