Wee1 Inhibitor
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WEE1-IN-4 (Standard)
0 ImagesCat. No.: HY-108343RCAS No.: 622855-37-2
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Sirusertib
0 ImagesCat. No.: HY-188057CAS No.: 3066062-53-8Sirusertib (WEE1A&Myt1-IN-1) is a dual Wee1A/Myt1 inhibitor, with an IC50 of ≤10 nM against Wee1A and ≤20 nM against Myt1. Sirusertib is applicable for cancer-related research.
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PKMYT1-IN-4
0 ImagesCat. No.: HY-162986CAS No.: 3047617-07-9PKMYT1-IN-4 (compund 27) is a PKMYT1 inhibitor with IC50 less than 50 nM.
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PKMYT1-IN-7
0 ImagesCat. No.: HY-159937CAS No.: 2986404-30-0PKMYT1-IN-7 (compound 7) is an orally active PKMYT1 inhibitor with IC50 values of 1.6 nM and 0.06 μM against of PKMYT1 and pCDK1, respectively. PKMYT1-IN-7 suppresses the phosphorylation of CDK1 at T14 and Y15. PKMYT1-IN-7 shows anticancer activity both
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Myt1-IN-6
0 ImagesCat. No.: HY-176853CAS No.: 3056083-14-5Myt1-IN-6 (Compound formula (1)) is a highly selective MYT1 kinase inhibitor. Myt1-IN-6 is promising for research of RB1-deficient cancers (e.g., triple-negative breast cancer).
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PKMYT1-IN-14
0 ImagesCat. No.: HY-184405PKMYT1-IN-14 is an allosteric, mixed ATP-competitive and non-competitive PKMYT1 inhibitor with an IC50 of 56.2 μM. PKMYT1-IN-14 is applicable to research related to breast cancer, gastric cancer, non-small cell lung cancer, and clear cell renal cell carcinoma.
