PKMYT1-IN-14
PKMYT1-IN-14 is an allosteric, mixed ATP-competitive and non-competitive PKMYT1 inhibitor with an IC50 of 56.2 μM. PKMYT1-IN-14 is applicable to research related to breast cancer, gastric cancer, non-small cell lung cancer, and clear cell renal cell carcinoma.
For research use only. We do not sell to patients.
- Formula: C17H19N3O2
- Molecular Weight:297.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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PKMYT1 56.2 μM (IC50) |
PKMYT1-IN-14 (Compound P29) (25 μM) binds to purified PKMYT1 kinase domain with an IC50 of 56.2 μM, displacing a fluorescent tracer by 43% at 25 μM[1].
PKMYT1-IN-14 (0-300 μM; 5 min preincubation, 40 min reaction) inhibits the kinase activity of purified PKMYT1 with a mixed competitive and noncompetitive mechanism, reducing activity across all tested ATP concentrations[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 297.35
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Formula C17H19N3O2
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SMILES
O=C1NC2=C(C=NN2C3CCCC3)[C@H](C4=CC=C(O)C=C4)C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PKMYT1-IN-14 Related Classifications
HY-184405 Related Classifications
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