2986404-30-0
Chemical Structure
PKMYT1-IN-7
- CAS. Nr.: 2986404-30-0
- Formula:C17H18FN5O3
- Molecular Weight:359.35
InChIKey: WYMHUHYVZWZYSY-UHFFFAOYSA-N
SMILES: O=C(C1=C(N)N(C2=C(C)C=CC(O)=C2C)C(N=C(C)N3CF)=C1C3=O)N
Biological Activity:
PKMYT1-IN-7 (compound 7) is an orally active PKMYT1 inhibitor with IC50 values of 1.6 nM and 0.06 μM against of PKMYT1 and pCDK1, respectively. PKMYT1-IN-7 suppresses the phosphorylation of CDK1 at T14 and Y15. PKMYT1-IN-7 shows anticancer activity both
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PKMYT1-IN-7 | PKMYT1-IN-7 (compound 7) is an orally active PKMYT1 inhibitor with IC50 values of 1.6 nM and 0.06 μM against of PKMYT1 and pCDK1, respectively. PKMYT1-IN-7 suppresses the phosphorylation of CDK1 at T14 and Y15. PKMYT1-IN-7 shows anticancer activity both |
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Keywords