2. Signaling Pathways
  3. Cell Cycle/DNA Damage
  4. Wee1
  5. PKMYT1 Isoform
  6. PKMYT1 Degrader

PKMYT1 Degrader

PKMYT1 Degrader (1):

Cat. No. Product Name Effect Purity
  • HY-180485
    PROTAC D16-M1P2
    		Degrader
    PROTAC D16-M1P2 is an orally active PKMYT1 PROTAC degrader with a DC50 of 0.7 nM. PROTAC D16-M1P2 also inhibits the activity of PKMYT1 with an IC50 of 7.6 nM. PROTAC D16-M1P2 inhibits pCDK1 with an IC50 of 9 nM. PROTAC D16-M1P2 has demonstrated significant anti-tumor efficacy in mouse models and can be used for research on breast cancer.