Amino Acid Oxidase Inhibitor

DAO-IN-2 is a d-amino acid oxidase (DAO) inhibitor (h-DAO IC₅₀ = 245 nM). DAO-IN-2 is a moderate inhibitor of DAAO in vitro and in vivo. DAO-IN-2 can be used to study DAAO-related psychiatric disorders.

AS057278 is a potent, selective, orally active and blood-brain barrier (BBB) penetrant non-peptidic D-amino acid oxidase (DAAO) inhibitor with an IC₅₀ value of 0.91 μM and EC₅₀ of 2.2-3.95 μM. AS057278 can normalize phencyclidine (PCP)-induced prepulse inhibition in mice. AS057278 can be used for researching schizophrenia.

1H-Indazol-5-ol is a porcine DAAO inhibitor with an IC₅₀ value of 2.03 μM. 1H-Indazol-5-ol can be used in the research of neurological disorders.

DAAO-IN-2 is a D-amino acid oxidase (DAAO) inhibitor, with an IC₅₀ of 0.123 μM against human DAAO and a K_d value of 1 μM against porcine DAAO. DAAO-IN-2 can be used for the research of schizophrenia.

AtPCO4-IN-1 is a selective inhibitor of AtPCO4 with an IC₅₀ of 264.4 μM.

DAO-IN-2 (Standard) is the analytical standard of DAO-IN-2 (HY-117292). This product is intended for research and analytical applications. DAO-IN-2 is a novel D-amino acid oxidase (DAO) inhibitor. DAO-IN-2 demonstrates moderate potency for DAO in vitro and ex vivo.

4,5,6,7-Tetrahydro-1,2-benzoxazole-3-carboxylic acid (Compound 244) is an indole compound. 4,5,6,7-Tetrahydro-1,2-benzoxazole-3-carboxylic acid does not inhibit COX-2 and shows the inhibition rate <1% against d-amino acid oxidase (DAO) at 10 μM.