39793-31-2
39793-31-2
Chemical Structure
DAO-IN-2
- CAS No.: 39793-31-2
- Formula:C7H5NO2S
- Molecular Weight:167.19
IUPAC Name: 4H-thieno[3,2-b]pyrrole-5-carboxylic acid
InChIKey: PMHDSACGRKBACK-UHFFFAOYSA-N
SMILES: O=C(C1=CC2=C(C=CS2)N1)O
Biological Activity: DAO-IN-2 is a d-amino acid oxidase (DAO) inhibitor (h-DAO IC50 = 245 nM). DAO-IN-2 is a moderate inhibitor of DAAO in vitro and in vivo. DAO-IN-2 can be used to study DAAO-related psychiatric disorders[1][2].
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DAO-IN-2 | 99.95% | DAO-IN-2 is a d-amino acid oxidase (DAO) inhibitor (h-DAO IC50 = 245 nM). DAO-IN-2 is a moderate inhibitor of DAAO in vitro and in vivo. DAO-IN-2 can be used to study DAAO-related psychiatric disorders. | ||||||||||||||||||||
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DAO-IN-2 (Standard) | ≥98% | DAO-IN-2 (Standard) is the analytical standard of DAO-IN-2 (HY-117292). This product is intended for research and analytical applications. DAO-IN-2 is a novel D-amino acid oxidase (DAO) inhibitor. DAO-IN-2 demonstrates moderate potency for DAO in vitro and ex vivo. | ||||||||||||||||||||
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References
- [1]. Tim Sparey, et, al. The discovery of fused pyrrole carboxylic acids as novel, potent D-amino acid oxidase (DAO) inhibitors. Bioorg Med Chem Lett. 2008,18, 11. [Content Brief]
- [2]. Smith SM, et al. The behavioral and neurochemical effects of a novel D-amino acid oxidase inhibitor compound 8 [4H-thieno [3,2-b]pyrrole-5-carboxylic acid] and D-serine. J Pharmacol Exp Ther. 2009 Mar;328(3):921-30. [Content Brief]
Keywords
