402-61-9
Chemical Structure
AS057278
- CAS No.: 402-61-9
- Formula:C5H6N2O2
- Molecular Weight:126.11
IUPAC Name: 5-methyl-1H-pyrazole-3-carboxylic acid
InChIKey: WSMQKESQZFQMFW-UHFFFAOYSA-N
SMILES: O=C(C1=NNC(C)=C1)O
Biological Activity: AS057278 is a potent, selective, orally active and blood-brain barrier (BBB) penetrant non-peptidic D-amino acid oxidase (DAAO) inhibitor with an IC50 value of 0.91 μM and EC50 of 2.2-3.95 μM. AS057278 can normalize phencyclidine (PCP)-induced prepulse inhibition in mice. AS057278 can be used for researching schizophrenia[1].
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AS057278 | 99.76% | AS057278 is a potent, selective, orally active and blood-brain barrier (BBB) penetrant non-peptidic D-amino acid oxidase (DAAO) inhibitor with an IC50 value of 0.91 μM and EC50 of 2.2-3.95 μM. AS057278 can normalize phencyclidine (PCP)-induced prepulse inhibition in mice. AS057278 can be used for researching schizophrenia. | ||||||||||||||||||||
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AS057278 (Standard) | ≥98% | AS057278 (Standard) is the analytical standard of AS057278. This product is intended for research and analytical applications. AS057278 is a potent, selective, orally active and blood-brain barrier (BBB) penetrant non-peptidic D-amino acid oxidase (DAAO) inhibitor with an IC50 value of 0.91 μM and EC50 of 2.2-3.95 μM. AS057278 can normalize phencyclidine (PCP)-induced prepulse inhibition in mice. AS057278 can be used for researching schizophrenia. | ||||||||||||||||||||
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Keywords