Amylin Receptor Inhibitor
-
Eloralintide sodium
0 ImagesCat. No.: HY-P10798APurity: 99.92%Synonyms: LY-3841136 sodiumEloralintide sodium is an Amylin Receptor agonist. Eloralintide sodium selectively activates AMY1R and AMY3R in cells expressing human or rat AMY1R, AMY3R or CTR. Eloralintide sodium activates AMYRs and CTR in rats, inducing a sustained decrease in plasma Ca2+ levels. Eloralintide sodium reduces appetite and body weight in both lean and obese rats. Eloralintide sodium can be used for research related to obesity.
-
NI-203
0 ImagesCat. No.: HY-P991249NI-203 is a monoclonal antibody inhibitor that targets amylin. NI-203 is promising for research of type 2 diabetes.
-
Cloridarol
0 ImagesCloridarol is a human islet amyloid peptide (hIAPP) inhibitor that prevents its abnormal misfolding and aggregation. Cloridarol can increase cell viability, inhibit apoptosis, and protect islet β-cells from hIAPP-induced cell toxicity. Cloridarol can be used for the research of type 2 diabetes (T2D).
-
Schizotenuin A
0 ImagesCat. No.: HY-N19921CAS No.: 144608-09-3Schizotenuin A is a Aβ and hIAPP fibrillation inhibitor with human-derived IC50 values of 2.93 µM and 0.58 µM, respectively, and exhibits antioxidant activity. Schizotenuin A scavenges DPPH free radicals and inhibits lipid peroxidation in rat liver microsomes. Schizotenuin A can be used in research related to Alzheimer's disease and type 2 diabetes.
