Calmodulin Inhibitor

Bromoriluzole is a derivative of Riluzole (HY-B0211). Bromoriluzole inhibits Ca²⁺ -dependent Calmodulin-SK4 channel interaction. Bromoriluzole is used for the research of neurodegenerative diseases.

Bisindolylmaleimide VII is a potent inhibitor of calmodulin with high affinity for calmodulin (K_d=186.2 nM). Bisindolylmaleimide VII is used to study the role of calmodulin in cancer, neurodegenerative diseases, and muscle dysfunction.

Metofenazate diethanesulfonate is a selective calmodulin inhibitor.

Quisultidine (LM 24056) is an orally active phenothiazine derivative with both calmodulin (Calmodulin) inhibitory activity (with a IC₅₀ of 55 μM against porcine calmodulin) and muscarinic acetylcholine receptor (mAChR) ligand activity (with a IC₅₀ of 400 nM). It inhibits gastric acid and pepsin secretion, reduces circulating gastrin levels, and blocks histamine-stimulated gastric acid secretion. Quisultidine can be used in the research of duodenal ulcer.

Propiverine (hydrochloride) (Standard) is the analytical standard of Propiverine (hydrochloride). This product is intended for research and analytical applications. Propiverine hydrochloride is a bladder spasmolytic with calcium antagonistic and anticholinergic properties. Propiverine hydrochloride can be used for the research of overactive blaqdder and urinary incontinence.