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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (10876):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B1776AS1
    Spermidine-13C4 hydrochloride
    Spermidine-13C4 (hydrochloride) is the 13C-labeled Spermidine trihydrochloride. Spermidine hydrochloride maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine hydrochloride significantly decreases the H2O2 and O2.- contents.
    Spermidine-<sup>13</sup>C<sub>4</sub> hydrochloride
  • HY-100355S1
    C18-Ceramide-d7
    99.0%
    C18-Ceramide-d7 is deuterium labeled C18-Ceramide.
    C18-Ceramide-d<sub>7</sub>
  • HY-B0932S
    Levocarnitine propionate-d3 hydrochloride
    98.89%
    Levocarnitine propionate-d3 (hydrochloride) is the deuterium labeled Levocarnitine propionate hydrochloride. Levocarnitine propionate hydrochloride (L-Propionylcarnitine chloride; ST-261) is used to treat the deterioration of renal function, congestive heart failure, intermittent claudication, and other diseases.
    Levocarnitine propionate-d<sub>3</sub> hydrochloride
  • HY-144243S
    Vitamin B5-d4 calcium
    99.17%
    Vitamin B5-d4 (calcium) is the deuterium labeled Vitamin B5 calcium.
    Vitamin B5-d<sub>4</sub> calcium
  • HY-W716965
    1,3-Diphenylguanidine-d10
    99.98%
    1,3-Diphenylguanidine-d10 is the deuterium labeled 1,3-Diphenylguanidine (HY-W014332). 1,3-diphenylguanidine is the primary and secondary accelerator in the vulcanization of rubber and is found in the rubber industry.
    1,3-Diphenylguanidine-d<sub>10</sub>
  • HY-N8015S
    Octanal-d16
    Octanal-d16 is the deuterium labeled Octanal. Octanal is a fragrant aldehyde with antioxidant and antibacterial activity. Its antifungal effect against G. citri-aurantii may be related to the disruption of cell membrane integrity and the leakage of cellular components. Additionally, Octanal exhibits cytotoxicity towards HeLa cells, with an IC50 value of 3.5 μg/mL.
    Octanal-d<sub>16</sub>
  • HY-N0230S2
    β-Alanine-d4
    99.90%
    β-Alanine-d4 is the deuterium labeled β-Alanine. β-Alanine is a non-essential amino acid that is shown to be metabolized into carnosine, which functions as an intracellular buffer.
    β-Alanine-d<sub>4</sub>
  • HY-N0097S6
    Guanosine-13C10,15N5
    99.8%
    Guanosine-13C10,15N5 is the 13C and 15N labeled Guanosine (HY-N0097). Guanosine (DL-Guanosine) is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity.
    Guanosine-<sup>13</sup>C<sub>10</sub>,<sup>15</sup>N<sub>5</sub>
  • HY-135170S
    Myristoyl-L-carnitine-d3 chloride
    99.94%
    Myristoyl-L-carnitine-d3 chloride is the deuterium labeled Myristoyl-L-carnitine chloride (HY-135170). Myristoyl-L-Carnitine Chloride is a natural long-chain glycoline, amino acid derivative.
    Myristoyl-L-carnitine-d<sub>3</sub> chloride
  • HY-W004284S
    Heptadecanoic acid-d3
    99.24%
    Heptadecanoic acid-d3 is the deuterium labeled Heptadecanoic acid. Heptadecanoic acid is an odd chain saturated fatty acid (OCS-FA). Heptadecanoic acid is associated with several diseases, including the incidence of coronary heart disease, prediabetes and type 2 diabetes as well as multiple sclerosis.
    Heptadecanoic acid-d<sub>3</sub>
  • HY-W009762S2
    L-Lysine-d4 dihydrochloride
    99.91%
    L-Lysine-d4 (dihydrochloride) is the deuterium labeled L-Lysine dihydrochloride.
    L-Lysine-d<sub>4</sub> dihydrochloride
  • HY-113472S
    N-Methyl-4-pyridone-3-carboxamide-d3
    99.63%
    N-Methyl-4-pyridone-3-carboxamide-d3 is deuterium labeled N-Methyl-4-pyridone-3-carboxamide.
    N-Methyl-4-pyridone-3-carboxamide-d<sub>3</sub>
  • HY-B1727S
    Phenanthrene-d10
    99.46%
    Phenanthrene-d10 is the deuterium labeled Phenanthrene. Phenanthrene is a polycyclic aromatic hydrocarbon (PAH) and has been frequently used as an indicator for monitoring PAH contaminated matrices. Phenanthrene induces oxidative stress and inflammation.
    Phenanthrene-d<sub>10</sub>
  • HY-N0667S3
    L-Asparagine-13C4 monohydrate
    98.9%
    L-Asparagine-13C4 monohydrate is the 13C-labeled L-Asparagine monohydrate (HY-W017443). L-Asparagine monohydrate is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine monohydrate can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia.
    L-Asparagine-<sup>13</sup>C<sub>4</sub> monohydrate
  • HY-15833S
    Chlorthalidone-d4
    98.49%
    Chlorthalidone-d4 is the deuterium labeled Chlorthalidone. Chlorthalidone is a thiazide-like diuretic used to treat hypertension.
    Chlorthalidone-d<sub>4</sub>
  • HY-Y0261AS1
    Ammonium sulphate,≥99.0%,AR-15N2
    99.30%
    Ammonium sulphate,≥99.0%,AR-15N2 is the deuterium labeled Ammonium sulphate,≥99.0%,AR. Ammonium sulphate,≥99.0%,AR is an inorganic sulfate salt used for molecular biology.
    Ammonium sulphate,≥99.0%,AR-<sup>15</sup>N<sub>2</sub>
  • HY-W013049S4
    Docosanoic acid-d4-1
    99.26%
    Docosanoic acid-d4-1 (Behenic acid-d4-1) is the deuterium labeled Docosanoic acid (HY-W013049). Docosanoic acid (Behenic acid) is a long-chain saturated fatty acid. Docosanoic acid inhibits the double-stranded DNA (dsDNA) binding activity of p53 DNA binding domain, with a Kd of 12 nM. Docosanoic acid has low bioavailability and can increase cholesterol in humans.
    Docosanoic acid-d<sub>4</sub>-1
  • HY-N0091S2
    Hypoxanthine-13C5
    98.0%
    Hypoxanthine-13C5 is a 13C-labeled Hypoxanthine (HY-N0091). Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.
    Hypoxanthine-<sup>13</sup>C<sub>5</sub>
  • HY-W727879
    Upadacitinib-15N,d2
    99.99%
    Upadacitinib-15N,d2 (ABT-494-15N,d2) is the deuterium-labeled Upadacitinib (HY-19569). Upadacitinib-15N,d2 (ABT-494) is a potent, orally active and selective Janus kinase 1 (JAK1) inhibitor (IC50=43 nM). Upadacitinib-15N,d2 (ABT-494) displays approximately 74 fold selective for JAK1 over JAK2 (200 nM) in cellular assays dependent on specific, relevant cytokines. Upadacitinib-15N,d2 (ABT-494) can be used for several autoimmune disorders research.
    Upadacitinib-<sup>15</sup>N,d<sub>2</sub>
  • HY-Y0378S
    D-Leucine-d10
    99.96%
    D-Leucine-d10 is the deuterium labeled D-Leucine. D-Leucine is a more potent anti-seizure agent than L-leucine. D-leucine potently terminates seizures even after the onset of seizure activity. D-leucine, but not L-leucine, reduces long-term potentiation but had no effect on basal synaptic transmission in vitro.
    D-Leucine-d<sub>10</sub>