Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Related Products (10873):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W750796

Butyric acid-¹³C₄ sodium		99.6%
Butyric acid-13C4 sodium (Butanoic acid-13C4 sodium) is a stable isotope labeled compound with the activity of promoting cell proliferation and regulating gene expression. Butyric acid-13C4 sodium can be used in metabolic research and compound development to help scientists gain a deeper understanding of the role of short-chain fatty acids in organisms. Butyric acid-13C4 sodium also plays an important role in nutrition and intestinal health research, especially in the regulation of probiotic function and intestinal microbiota.

HY-118877

Urea-¹³C		99.60%
Urea-¹³C is the ¹³C labelled urea. The Urea-¹³C breath test (¹³C-UBT) is one of the best methods for the diagnosis of Helicobacter pylori infection.

HY-113225S5

Guanosine triphosphate-¹³C₁₀ dilithium		99.4%
Guanosine triphosphate-¹³C₁₀ (GTP-¹³C₁₀) dilithium is ¹³C-labeled Guanosine triphosphate (HY-113225). Guanosine triphosphate dilithium (GTP) is a critical nucleotide and regulator of cellular metabolism. Guanosine triphosphate dilithium promotes ribosomal DNA localization, pre-rRNA transcription and ribosome biogenesis by binding to RNA polymerase I and GPN proteins (GPN1/3). Guanosine triphosphate dilithium links MYC-dependent ribosome biogenesis to nucleotide sufficiency, acts as a metabolic gatekeeper supporting protein synthesis, DNA/RNA synthesis and cellular signal transduction, while also participating in the physiological activities of pancreatic β-cells and serving as an oxidative substrate for reactive oxygen species. In small cell lung cancer with high MYC expression, Guanosine triphosphate dilithium accumulates through the IMPDH-driven synthetic pathway, thereby affecting apoptosis and mitotic processes. Guanosine triphosphate dilithium is used in the research of small cell lung cancer, hepatoblastoma and cellular metabolism.

HY-B1337S3

Choline-d₁₃ chloride		99.90%
Choline-d₁₃ (chloride) is the deuterium labeled Choline chloride. Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens where it accelerates growth.

HY-W718300

Indole-3-pyruvic acid-d₅
Indole-3-pyruvic acid-d₅ is deuterated labeled Indole-3-pyruvic acid. Indole-3-pyruvic acid, a keto analogue of tryptophan, is an orally active AHR agonist. Indole-3-pyruvic acid has antioxidant properties, and can be used in the research of inflammation, anxiety.

HY-N0086S1

N6-Methyladenosine-¹³C		99.91%
N6-Methyladenosine-¹³C is the ¹³C labeled isotope of N6-Methyladenosine.

HY-W127572

Glycerol-d₈		99.98%
Glycerol-d₈ is the deuterium labeled Glycerol.

HY-15917S2

DL-Dithiothreitol-d₆		98.73%
DL-Dithiothreitol-d₆ is the deuterated form of DL-Dithiothreitol. DL-dithiothreitol (DTT) is a strong reductant with anti-disulfidptosis activity. DL-dithiothreitol is oxidized to form a stable six-membered ring with an internal disulfide bond.

HY-W010981S

Acetyl tributyl citrate-d₃		99.78%
Acetyl tributyl citrate-d₃ (Tributyl O-acetylcitrate-d₃) is the deuterium labeled Acetyl tributyl citrate (HY-W010981). Acetyl tributyl citrate can be used in cosmetics, food packaging, and as a flavoring substance for food.

HY-W013940S1

DL-Cystine-d₆		99.96%
DL-Cystine-d₆ is the deuterium labeled DL-Cystine (HY-W013940). DL-Cystine is a cysteine derivative.

HY-W012722BS1

4-Methyl-2-oxopentanoic acid-¹³C sodium		99.75%
4-Methyl-2-oxopentanoic acid-¹³C (sodium) is the ¹³C labeled 4-Methyl-2-oxopentanoic acid sodium.

HY-Y0546S

Benzophenone-d₁₀		99.63%
Benzophenone-d₁₀ is the deuterium labeled Benzophenone (HY-Y0546). Benzophenone is an endogenous metabolite. Benzophenone is a photosensitizer, that absorbs UV light, transfers its energy to DNA, and triggers DNA damage. Benzophenone can be used as the fragrance enhancer, ultraviolet curing agent, additive in plastics, or the flavor ingredient. Benzophenone can also be used in the manufacturing of insecticides, agricultural chemicals, hypnotics, antihistamines, and other pharmaceuticals. Benzophenone exhibits certain carcinogenicity in mouse/rat models under long term exposure. Benzophenone exhibits estrogenic activity.

HY-151003S

D-Panthenol-d₄		99.77%
D-Panthenol-d₄ is the deuterium labeled D-Panthenol.

HY-W013049S3

Docosanoic acid-d₃		99.00%
Docosanoic acid-d₃ (Behenic acid-d₃) is the deuterium labeled Docosanoic acid (HY-W013049). Docosanoic acid (Behenic acid) is a long-chain saturated fatty acid. Docosanoic acid inhibits the double-stranded DNA (dsDNA) binding activity of p53 DNA binding domain, with a K_d of 12 nM. Docosanoic acid has low bioavailability and can increase cholesterol in humans.

HY-132382S

β-Sitosterol-d₇ (Mixture of Diastereomers)		98.0%
β-Sitosterol-d₇ (Mixture of Diastereomers) is the deuterium labeled β-Sitosterol (mixture of diasteromers).

HY-10219S

Rapamycin-d₃
Rapamycin-d₃ is the deuterium labeled Rapamycin. Rapamycin is a potent and specific mTOR inhibitor with an IC₅₀ of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant.

HY-13740S

Resiquimod-d₅		98.33%
Resiquimod-d₅ is deuterium labeled Resiquimod. Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α.

HY-W010388AS

Creatine-d₃ hydrate		99.00%
Creatine-d₃ (hydrate) is a deuterium labeled Creatine hydrate. Creatine hydrate is pivotal in energy metabolism of muscle and brain cells, both in physiological and in pathological conditions.

HY-132436S

4’-Hydroxy Flurbiprofen-d₃		99.23%
4’-Hydroxy Flurbiprofen-d₃ is the deuterium labeled 4’-Hydroxy Flurbiprofen.

HY-12033S2

2-Methoxyestradiol-d₅		98.67%
2-Methoxyestradiol-d₅ is the deuterium labeled 2-Methoxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa.

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