Liposome

Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.

References:

[1]. Almeida B, Nag OK, Rogers KE, Delehanty JB. Recent Progress in Bioconjugation Strategies for Liposome-Mediated Drug Delivery. Molecules. 2020;25(23):5672. Published 2020 Dec 1. [Content Brief]

Productos relacionados con Liposome (1007):

By Effects:	Inhibitors (2) Controls (2) Substrate (1) Modulator (1) Chemicals (8)

Cat. No.	Nombre del producto	Efecto	Pureza	Chemical Structure

HY-144005A

C16 PEG750 Ceramide
C16 PEG750 Ceramide (C16 PEG Ceramide (MW 750)) is a PEG lipid for the preparation of liposomes and can be used in drug delivery studies.

HY-N15843

Chol-mPEG2000
Chol-mPEG2000 is a PEG lipid containing cholesterol and can be used to prepare lipid nanoparticles for drug delivery.

HY-W1130459

(R)-C12-200
(R)-C12-200 is the (R)-isomer of C12-200 (HY-145405), an ionizable cationic lipid and helper lipid. (R)-C12-200 enables functional mRNA delivery to head and neck squamous cell carcinoma xenograft tumor cells in NU/J immunocompromised mice, with minimal off-target delivery to liver or spleen. (R)-C12-200 can be utilized in the formation of lipid nanoparticles and mRNA delivery.

HY-172274A

DSPE-PEG2000-Mal-Cys-APRPG
DSPE-PEG2000-APRPG is a PEG compound which composed of DSPE and a APRPG peptide. DSPE-PEG2000-APRPG can be used for drug delivery.

HY-172283B

DSPE-PEG5000-BR2
DSPE-PEG5000-BR2 is a PEG compound which composed of DSPE and a BR2. BR2 is a targeting peptide composed of 17 amino acids with the sequence RAGLQFPVGRLLRRLLR. It has the ability to assist cells to penetrate the membrane and can specifically target certain cells or tissues.

HY-144019

18:0 EPC chloride
18:0 EPC chloride is a synthetic cationic phospholipid. 18:0 EPC chloride (at the critical synergistic concentrations of 2.34-2.93 μM) significantly improves the inactivation effect of eugenol against Escherichia coli.

HY-172273C

DSPE-PEG3400-M2pep
DSPE-PEG3400-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG3400-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery.

HY-153375

LNP Lipid-5
LNP Lipid-5 (Compound Lipid 2) is an ionizable lipid (amino lipid). LNP Lipid-5 can be used to prepare lipid nanoparticles (LNP).

HY-172336

4-O10b1
4-O10b1 is an ionizable cationic lipid. 4-O10b1 can be used to prepare lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo.

HY-172015

CP-LC-1143
CP-LC-1143 is an ionizable cationic amino lipid efficient delivery of different kinds of RNA (mRNA, cRNA and saRNA).

HY-172703

DSPE-PEG5000-NYZL1
DSPE-PEG5000-NYZL1 is a PEG compound which composed of DSPE and a NYZL1 peptide. NYZL1 can specifically bind to bladder cancer tissues and cells. DSPE-PEG5000-NYZL1 can be used for drug delivery.

HY-176509H

DSPE-PEG40000-CHO
DSPE-PEG40000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG40000-CHO can be used for drug delivery.

HY-182100C

DSPE-PEG5000-MTP
DSPE-PEG5000-MTP is a PEG compound which composed of DSPE and a muscle-targeting peptide (MTP). MTP is a muscle-targeting peptide with the property of targeting muscle tissue. DSPE-PEG5000-MTP can be used for drug delivery.

HY-112773

1,1′,1′′,1′′′-[1,4-Piperazinediylbis(2,1-ethanediylnitrilo)]tetrakis[2-dodecanol]		98.0%
1,1′,1′′,1′′′-[1,4-Piperazinediylbis(2,1-ethanediylnitrilo)]tetrakis[2-dodecanol] is a lipid/lipidoid used in preparation of lipid-based or lipidoid nanoparticles.

HY-172501

DSPE-PEG5000-Mal-CLPLIPTHIISFS
DSPE-PEG5000-Mal-CLPLIPTHIISFS is a PEG compound composed of DSPE and the liver cancer targeting peptide SP94 (HY-P11050A) (sequence SFSIIHTPILPL). SP94 exhibits specific binding to hepatocellular carcinoma (HCC) cells. DSPE-PEG5000-Mal-CLPLIPTHIISFS can be used to prepare lipid nanoparticles to form liver cancer-targeting nanocarriers.

HY-145742S

1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol-d₇₀ sodium
1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol-d₇₀ (sodium) is deuterium labeled 1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol. 1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol (sodium) is the component of liposomes for drug delivery.

HY-W1130458

503O8,12
503O8,12 is an ionizable cationic lipidoid that enables mRNA delivery to the spleen and lungs in mice when formulated into lipid nanoparticles with neutral helper lipid DOPE[1].

HY-167936

cis-AY 9944	Inhibitor
cis-AY 9944 is a cholesterol synthesis inhibitor, exhibiting anticonvulsant activity that influences the dynamics of spike and wave discharges in EEG recordings.

HY-113217F

BODIPY 480/508-cholesteryl oleate
BODIPY 480/508-cholesteryl oleate is a fluorescently tagged derivative of Cholesteryl oleate (HY-113217). BODIPY 480/508-cholesteryl oleate can be used to monitor lipid transport mechanisms in mammalian cells (Ex/Em = 480/508 nm).

HY-116585

C6 D-Threo Ceramide (d18:1/6:0)
C6 D-Threo Ceramide (d18:1/6:0) is a bioactive sphingolipid and cell-permeable analog of ceramides. C6 D-Threo Ceramide (d18:1/6:0) enhances IL-4 production induced by Phorbol 12-myristate 13-acetate (HY-18739) in EL4 T cells.

Name
E-mail *

	Sorry, but the email address you supplied was invalid.