Liposome
Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.
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Liposome Related Products (1266)
Related Products (1266)
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TCL065
0 ImagesCat. No.: HY-176754CAS No.: 1872269-57-2TCL065 is an ionizable lipid with a pKa of 6.3. TCL065 can be used to generate lipid nanoparticles (LNPs) for the delivery of mRNA as well as single-guide RNA (sgRNA) both in vitro and in vivo. TCL065-containing LNPs can studied in research for Duchenne muscular dystrophy and gene-editing technologies.
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DSPE-PEG1000-THRPPMWSPVWP
0 ImagesCat. No.: HY-172689DSPE-PEG1000-THRPPMWSPVWP is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (THRPPMWSPVWP). THRPPMWSPVWP binds to the TfR and is subsequently internalized into TfR-expressing cells.
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MR-2-93-3
0 ImagesCat. No.: HY-160582CAS No.: 2941228-90-4Synonyms: RML-1MR-2-93-3 is a long-chain fatty acid that can be used to deliver polynucleotides.
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DMG-PEG2000-Galactose
0 ImagesCat. No.: HY-183196ADMG-PEG2000-Galactose is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and terminal galactose. DMG-PEG2000-Galactose combines the membrane compatibility of phospholipids with the targeted recognition capabilities of galactose, making it suitable for research in biomaterial construction and drug delivery.
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C16-18:1 PE
0 ImagesCat. No.: HY-174286CAS No.: 119904-40-4C16-18:1 PE is a lipid. C16-18:1 PE has the activity of promoting membrane fusion and enhancing endosomal escape, which can significantly improve the delivery efficiency of mRNA. C16-18:1 PE is used in the synthesis of lipid nanoparticles (LNP).
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PI(3,5)P2 diC16
0 ImagesCat. No.: HY-148972CAS No.: 214282-36-7PI(3,5)P2 diC16 is a synthetic inositol phospholipid. PI(3,5)P2 diC16 is a lipid molecule.
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50-C2-C9-4tail
0 ImagesCat. No.: HY-153371CAS No.: 1853203-01-650-C2-C9-4tail has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA and mRNA in vitro and in vivo.
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(S)-O12-D3-I3
0 ImagesCat. No.: HY-172328ACAS No.: 3041009-08-6(S)-O12-D3-I3 is an ionizable cationic lipid (pKa = 6.39). (S)-O12-D3-I3 can be used to prepare lipid nanoparticles (LNPs) for in vitro and in vivo siRNA delivery. (S)-O12-D3-I3 can also be used in research on cancers such as liver cancer and breast cancer.
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DPPE-PEG3400-Mal
0 ImagesCat. No.: HY-W1052492ADPPE-PEG3400-Mal is a conjugate composed of DPPE, PEG chains, and maleimide (Mal). The maleimide group in DPPE-PEG3400-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
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DSG-PEG10000-Glucose
0 ImagesCat. No.: HY-183159DDSG-PEG10000-Glucose is a conjugate composed of DSG, a PEG chain, and terminal glucose. DSG-PEG10000-Glucose combines the membrane compatibility of phospholipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
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DSPE-PEG1000-GRGDS
0 ImagesCat. No.: HY-172683DSPE-PEG1000-GRGDS is a PEG compound which composed of DSPE and an anti-adhesion peptide (GRGDS). GRGDS can block the binding and adhesion of extracellular matrix to cell surface integrins. DSPE-PEG1000-GRGDS can be used for drug delivery.
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DOG-IM4
0 ImagesCat. No.: HY-160577CAS No.: 2758097-38-8DOG-IM4 can be used to synthesize nanoparticles to deliver antigen-encoding nucleic acids. It could be used to try to target autoimmune diseases, rare blood or metabolic diseases, allergies, cancer or infectious diseases.
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Palmitoyloleoylphosphatidylglycerol
0 ImagesCat. No.: HY-142982CAS No.: 81490-05-3Palmitoyloleoylphosphatidylglycerol is an anionic surfactant lipid. Palmitoyloleoylphosphatidylglycerol suppresses Der p 2-stimulated inflammatory responses in lung epithelial cells and macrophages.
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DOPE-PEG(2000)-HALO-TAG ammonium
0 ImagesCat. No.: HY-N16036CAS No.: 2342575-90-8DOPE-PEG(2000)-HALO-TAG ammonium is a PEG polymer containing unsaturated DOPE phospholipids. DOPE-PEG(2000)-HALO-TAG ammonium can be used to prepare liposomes or other nanoparticles for drug delivery.
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DMG-PEG3400-Alkyne
0 ImagesCat. No.: HY-183191BDMG-PEG3400-Alkyne is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and a terminal alkyne group. DMG-PEG3400-Alkyne combines the membrane compatibility of phospholipids with the high reactivity of the alkyne group in click chemistry, making it suitable for research in biomaterial construction and drug delivery.
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18:0 mPEG3000 PE ammonium
0 ImagesCat. No.: HY-144013ECAS No.: 474922-77-5Synonyms: DSPE-mPEG3000 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammonium18:0 mPEG3000 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
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DSPE-PEG1000-SPDP
0 ImagesCat. No.: HY-W440899DSPE-PEG1000-SPDP is a thiol reactive PEG lipid. The polymer is amphiphilic and spontaneously forms lipid bilayer in water. It can be used to encapsulate nutrients or therapeutics for targeted drug delivery, for example mRNA or DNA vaccine, liposomal doxorubicin for anti tumor.
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DSPE-PEG2000-TAASGVRSMH
0 ImagesCat. No.: HY-172482DSPE-PEG2000-TAASGVRSMH is a PEG compound which composed of DSPE and TAASGVRSMH. TAASGVRSMH has a strong affinity for the NG2 proteoglycan on the PC membrane. DSPE-PEG2000-TAASGVRSMH can be used for drug delivery.
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DSG-PEG2000-CHO
0 ImagesCat. No.: HY-183171ADSG-PEG2000-CHO is a conjugate composed of DSG, a PEG chain, and a terminal aldehyde group (-CHO). DSG-PEG2000-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.
