1872269-57-2
1872269-57-2
Chemical Structure
TCL065
- CAS No.: 1872269-57-2
- Formula:C51H97NO8
- Molecular Weight:852.32
InChIKey: IRCNKFFTLQSCTC-UHFFFAOYSA-N
SMILES: O=C(CCCCN(C)C)OCC(COC(CC(CCCCC)CCCCC)=O)(COC(CC(CCCCC)CCCCC)=O)COC(CC(CCCCC)CCCCC)=O
Biological Activity: TCL065 is an ionizable lipid with a pKa of 6.3. TCL065 can be used to generate lipid nanoparticles (LNPs) for the delivery of mRNA as well as single-guide RNA (sgRNA) both in vitro and in vivo. TCL065-containing LNPs can studied in research for Duchenne muscular dystrophy and gene-editing technologies[1].
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TCL065 | TCL065 is an ionizable lipid with a pKa of 6.3. TCL065 can be used to generate lipid nanoparticles (LNPs) for the delivery of mRNA as well as single-guide RNA (sgRNA) both in vitro and in vivo. TCL065-containing LNPs can studied in research for Duchenne muscular dystrophy and gene-editing technologies. | |||||||||||||||||||||
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