2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Sialyltransferase
  5. ST6Gal Isoform
  6. ST6Gal Inhibitor

ST6Gal Inhibitor

ST6Gal Inhibitor (1):

Cat. No. Product Name Effect Purity
  • HY-163548
    SPP-002
    		Inhibitor 98.0%
    SPP-002 is a ST6GAL1 inhibitor with a human IC50 of 16.7 μM. SPP-002 selectively inhibits N-glycan sialylation over O-glycan sialylation and binds strongly to the enzyme active site. SPP-002 suppresses expression of signaling proteins in the integrin/FAK/paxillin pathway. SPP-002 can be used for the research of triple negative breast cancer metastasis.