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Cat. No.: HY-169357B

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Acepromazine-1-piperazinepropanamine dihydrochloride

Name: Acepromazine-1-piperazinepropanamine dihydrochloride
Brand: MedChemExpress
SKU: HY-169357B
Price: 280.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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Acepromazine-1-piperazinepropanamine dihydrochloride (compound 10) is a synthesized E3 ligase ligand-linker conjugate (E3 Ligase Ligand-Linker Conjugate) that incorporates a TRIM21 ligand and a linker. Acepromazine-1-piperazinepropanamine dihydrochloride can be connected to the target protein ligand to form a PROTAC molecule, TrimTAC1 (HY-169355).

For research use only. We do not sell to patients.

Purity : 99.46%
Formula: C₂₄H₃₄Cl₂N₄OS
Molecular Weight:497.52

Storage:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

Acepromazine-1-piperazinepropanamine dihydrochloride Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
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Biological Activity

Description

All E3 Ligase Ligand-Linker Conjugates Isoforms :

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Appearance Solid
Molecular Weight 497.52
Formula C₂₄H₃₄Cl₂N₄OS
Color Light yellow to yellow
SMILES

NCCCN1CCN(CCCN2C(C=CC=C3)=C3SC4=C2C=C(C(C)=O)C=C4)CC1.Cl.Cl
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Panrui Lu, et al. Selective degradation of multimeric proteins by TRIM21-based molecular glue and PROTAC degraders. Cell. 2024 Oct 30:S0092-8674(24)01197-8. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Acepromazine-1-piperazinepropanamine dihydrochloride

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Biological Activity
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Acepromazine-1-piperazinepropanamine dihydrochloride

All E3 Ligase Ligand-Linker Conjugates Isoforms

Biological Activity

Description

In Vitro

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Acepromazine-1-piperazinepropanamine dihydrochloride Related Classifications

HY-169357B Related Classifications

Bioz

Keywords

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