Acepromazine-1-piperazinepropanamine dihydrochloride

Name: Acepromazine-1-piperazinepropanamine dihydrochloride
Brand: MedChemExpress
SKU: HY-169357B
Rating: 4.5 (0 reviews)

Cat. No.: HY-169357B Pureza: 99.46%: Ficha de datos
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Acepromazine-1-piperazinepropanamine dihydrochloride (compound 10) is a synthesized E3 ligase ligand-linker conjugate (E3 Ligase Ligand-Linker Conjugate) that incorporates a TRIM21 ligand and a linker. Acepromazine-1-piperazinepropanamine dihydrochloride can be connected to the target protein ligand to form a PROTAC molecule, TrimTAC1 (HY-169355).

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Acepromazine-1-piperazinepropanamine dihydrochloride Estructura química

Tamaño	Stock	Cantidad
5 mg	En stock	Estimated Time of Arrival: December 31
10 mg	En stock	Estimated Time of Arrival: December 31
25 mg	En stock	Estimated Time of Arrival: December 31
50 mg	En stock	Estimated Time of Arrival: December 31
100 mg	En stock	Estimated Time of Arrival: December 31
200 mg	Obtener un presupuesto
500 mg	Obtener un presupuesto

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Based on 1 Customer Validation

Other Forms of Acepromazine-1-piperazinepropanamine dihydrochloride:

Acepromazine-1-piperazinepropanamine Obtener un presupuesto

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Ver todos los productos específicos de isoformas E3 Ligase Ligand-Linker Conjugates:

Ver todas las isoformas

von Hippel-Lindau (VHL) MDM2 Cereblon cIAP1 Aryl Hydrocarbon Receptor TRIM21

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Descripciòn

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

497.52

Fòrmula

C₂₄H₃₄Cl₂N₄OS

Appearance

Solid

Color

Light yellow to yellow

SMILES

NCCCN1CCN(CCCN2C(C=CC=C3)=C3SC4=C2C=C(C(C)=O)C=C4)CC1.Cl.Cl

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Pureza y Documentación

Purity: 99.46%

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Ficha de datos (268 KB) SDS (251 KB)

COA (249 KB) HNMR (150 KB) RP-HPLC (145 KB) LCMS (111 KB)

Instrucciones de manejo (2659 KB)

Referencias

[1]. Panrui Lu, et al. Selective degradation of multimeric proteins by TRIM21-based molecular glue and PROTAC degraders. Cell. 2024 Oct 30:S0092-8674(24)01197-8. [Content Brief]