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Cat. No.: HY-W016586AR

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Acivicin hydrochloride (Standard)

(Synonyms: AT-125 hydrochloride (Standard); U-42126 hydrochloride (Standard))

Acivicin (hydrochloride) (Standard) is the analytical standard of Acivicin (hydrochloride). This product is intended for research and analytical applications. Acivicin hydrochloride (AT-125 hydrochloride), a natural product produced by Streptomyces sviceus, is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin hydrochloride can across the blood-brain barrier and has anti-cancer, anti-parasitic properties[1][2].

For research use only. We do not sell to patients.

CAS No.: 161922-40-3
Formula: C₅H₈Cl₂N₂O₃
Molecular Weight:215.03

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Acivicin hydrochloride (Standard) Chemical Structure

CAS No.: 161922-40-3

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Product Information
- Information
- Application
Chemical Information
Purity & Documentation
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Bioz

Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 161922-40-3
Molecular Weight 215.03
Formula C₅H₈Cl₂N₂O₃
SMILES

[H]Cl.ClC1=NO[C@@]([C@H](N)C(O)=O)([H])C1
Synonyms

AT-125 hydrochloride (Standard); U-42126 hydrochloride (Standard)
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
- Microorganisms
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Kreuzer J, et al. Target discovery of acivicin in cancer cells elucidates its mechanism of growth inhibition. Chem Sci. 2014 Dec 1;6(1):237-245. Epub 2014 Sep 26. [Content Brief]

[2]. Chikhale EG, et al. Carrier-mediated transport of the antitumor agent acivicin across the blood-brain barrier. Biochem Pharmacol. 1995 Mar 30;49(7):941-5. [Content Brief]

[3]. Delphine Waniusiow, et al. Toluene-induced hearing loss in acivicin-treated rats. Neurotoxicol Teratol. May-Jun 2008;30(3):154-60. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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