2. Metabolic Enzyme/Protease
  3. Glycosidase
  4. α-Glucosidase-IN-112

α-Glucosidase-IN-112 is an α-glucosidase inhibitor with an IC50 of 2.03 μM and a Ki of 0.44 μM. α-Glucosidase-IN-112 exerts antioxidant effects by scavenging ABTS+ free radicals. α-Glucosidase-IN-112 exerts antiproliferative effects by inhibiting the proliferation of bladder cancer cells. α-Glucosidase-IN-112 can be used in research related to type 2 diabetes and bladder cancer.

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α-Glucosidase-IN-112

α-Glucosidase-IN-112 화학구조

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α-Glucosidase-IN-112 Related Antibodies

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제품 설명

α-Glucosidase-IN-112 is an α-glucosidase inhibitor with an IC50 of 2.03 μM and a Ki of 0.44 μM. α-Glucosidase-IN-112 exerts antioxidant effects by scavenging ABTS+ free radicals. α-Glucosidase-IN-112 exerts antiproliferative effects by inhibiting the proliferation of bladder cancer cells. α-Glucosidase-IN-112 can be used in research related to type 2 diabetes and bladder cancer[1].

IC50 & Target[1]

α‑glucosidase

2.03 μM (IC50)

α‑glucosidase

0.44 μM (Ki)

In Vitro

α-Glucosidase-IN-112 (Compound 4i) (0-2.0 μM; 24 h) potently inhibits the proliferation of human T24 bladder cancer cells with an IC50 of 1.93 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

α-Glucosidase-IN-112 Related Antibodies

Cell Proliferation Assay[1]

Cell Line: human T24 bladder cancer cells
Concentration: 0, 0.5, 1, 1.5 and 2.0 μM
Incubation Time: 24 h
Result: Inhibited T24 bladder cancer cell proliferation with an IC50 value of 1.93 μM, which is lower than the IC50 value of the positive control cisplatin.
분자량

466.58

화학식

C23H22N4O3S2
SMILES

O=S(C1=CC=C(/C(C)=N/NC(C2=CNC3=C2C=CC=C3)=O)C=C1)(NCCC4=CC=CS4)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
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α-Glucosidase-IN-112 Related Classifications

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  • 농도 희석 계산기

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

α-Glucosidase-IN-112Glycosidasetype-2 diabetesSaccharomyces cerevisiaebladder cancer cellsα-glucosidaseMM/PBSA binding free energybladder cancerhuman T24 bladder cancer cellsamino acid residuesABTS+ free radicalsactive siteInhibitorinhibitorinhibit

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상품명:
α-Glucosidase-IN-112
Cat. No.:
HY-181353
수량:
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