α-Glucosidase-IN-112
α-Glucosidase-IN-112 is an α-glucosidase inhibitor with an IC50 of 2.03 μM and a Ki of 0.44 μM. α-Glucosidase-IN-112 exerts antioxidant effects by scavenging ABTS+ free radicals. α-Glucosidase-IN-112 exerts antiproliferative effects by inhibiting the proliferation of bladder cancer cells. α-Glucosidase-IN-112 can be used in research related to type 2 diabetes and bladder cancer.
For research use only. We do not sell to patients.
- Formula: C23H22N4O3S2
- Molecular Weight:466.58
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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α‑glucosidase 2.03 μM (IC50) |
α‑glucosidase 0.44 μM (Ki) |
α-Glucosidase-IN-112 (Compound 4i) (0-2.0 μM; 24 h) potently inhibits the proliferation of human T24 bladder cancer cells with an IC50 of 1.93 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:human T24 bladder cancer cells
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Concentration:0, 0.5, 1, 1.5 and 2.0 μM
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Incubation Time:24 h
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Result:Inhibited T24 bladder cancer cell proliferation with an IC50 value of 1.93 μM, which is lower than the IC50 value of the positive control cisplatin.
Chemical Information
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Molecular Weight 466.58
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Formula C23H22N4O3S2
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SMILES
O=S(C1=CC=C(/C(C)=N/NC(C2=CNC3=C2C=CC=C3)=O)C=C1)(NCCC4=CC=CS4)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
α-Glucosidase-IN-112 Related Classifications
HY-181353 Related Classifications
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