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Cat. No.: HY-P991998

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Anti-Human/Monkey CD16a Antibody (3G8)

Anti-Human/Monkey CD16a Antibody (3G8) is a monoclonal antibody targeting CD16a. Anti-Human/Monkey CD16a Antibody (3G8) blocks FcγRIII/CD16a, upregulates the metabolic activity of CD16+ cells, downregulates CD87, a poor prognostic marker, and inhibits the engraftment and growth of leukemia cells in acute myeloid leukemia, and rapidly increases platelet counts in immune thrombocytopenia. Anti-Human/Monkey CD16a Antibody (3G8) is applicable to research related to tumor immunology.

For research use only. We do not sell to patients.

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Anti-Human/Monkey CD16a Antibody (3G8) Chemical Structure

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Anti-Human/Monkey CD16a Antibody (3G8) Product Recommendations:

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Isotype
- Recommend Isotype Controls
- Species Reactivity
- In Vitro
- In Vivo
- Gene ID
- Accession
- Target
- Conjugated
- Reconsititution
- Format
- Application
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Isotype

Mouse IgG1 kappa

Recommend Isotype Controls

Mouse IgG1 kappa, Isotype Control

Species Reactivity

Human/Monkey

In Vitro

Anti-Human/Monkey CD16a Antibody (3G8) increases the metabolic activity of CD16a+ MOLM-13 acute myeloid leukemia cell cultures^[1].
Anti-Human/Monkey CD16a Antibody (3G8) (24 h) induces CD16a+ MOLM-13 acute myeloid leukemia cells to downregulate the unfavorable prognostic marker CD87^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Anti-Human/Monkey CD16a Antibody (3G8) inhibits engraftment of CD16a+ MOLM-13 acute myeloid leukemia cells in NSG mice^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Gene ID

2214 [NCBI]

Accession

P08637

Target

CD16a

Conjugated

Unconjugated

Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.

Format

Product Image

Application

ELISA, FACS, Functional assay

Chemical Information

SMILES

[Anti-Human/Monkey CD16a Antibody (3G8)]
Formulation

Please refer to the lot-specific COA for specific buffer information.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Inhibitory Antibodies User Guide (603 KB)

References

[1]. Prada B D. Uncovering the Functionality of CD16a on Acute Myeloid Leukemia Cells. Icahn School of Medicine at Mount Sinai, 2023.

[2]. Xu M, Feng Q, et al. Blocking FcγRIII with anti-CD16 mab (3G8 and GMA161) increases platelets in immune thrombocytopenia: Two pilot studies. Blood, 2025, 146: 4821.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Anti-Human/Monkey CD16a Antibody (3G8)

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Amount: USD 0.00

Biological Activity
- Description
- Isotype
- Recommend Isotype Controls
- Species Reactivity
- In Vitro
- In Vivo
- Gene ID
- Accession
- Target
- Conjugated
- Reconsititution
- Format
- Application
Chemical Information
Purity & Documentation
References

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MCE Japan Authorized Agent:

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Anti-Human/Monkey CD16a Antibody (3G8)

PBS Buffer (1×)

Cytotoxicity LDH Assay Kit

DPBS Buffer (1×)

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Anti-Human/Monkey CD16a Antibody (3G8) Related Classifications

HY-P991998 Related Classifications

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